EPH Receptor B2 antibody (C-Term)
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- Target See all EPH Receptor B2 (EPHB2) Antibodies
- EPH Receptor B2 (EPHB2)
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Binding Specificity
- AA 1021-1050, C-Term
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This EPH Receptor B2 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)
- Purification
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
- Immunogen
- This EphB2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1021-1050 amino acids from the C-terminal region of human EphB2.
- Clone
- RB01652
- Isotype
- Ig Fraction
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anti-EPH Receptor B2 (EPHB2) antibody
EPHB2 Reactivity: Human WB, ELISA, IHC, FACS Host: Mouse Monoclonal 48CT12-6-4 unconjugated
anti-EPH Receptor B2 (EPHB2) (AA 551-650) antibodyEPHB2 Reactivity: Human, Mouse, Rat WB, ELISA, FACS, IHC (p), IF (cc), IHC (fro), IF (p) Host: Rabbit Polyclonal unconjugated
anti-EPH Receptor B2 (EPHB2) (AA 103-133), (N-Term) antibodyEPHB2 Reactivity: Human, Mouse IHC (p) Host: Rabbit Polyclonal RB01650 unconjugated
anti-EPH Receptor B2 (EPHB2) antibodyEPHB2 Reactivity: Human WB, FACS, IHC (p) Host: Rabbit Polyclonal RB15188 unconjugated
anti-EPH Receptor B2 (EPHB2) antibodyEPHB2 Reactivity: Human WB, FACS, IHC (p) Host: Mouse Monoclonal 48CT12-6-4 unconjugated
anti-EPH Receptor B2 (EPHB2) (AA 17-200) antibodyEPHB2 Reactivity: Human WB, ELISA, ICC Host: Mouse Monoclonal 2D12C6 unconjugated
anti-EPH Receptor B2 (EPHB2) (AA 226-325) antibodyEPHB2 Reactivity: Human WB, ELISA Host: Mouse Monoclonal 4D1 unconjugated
anti-EPH Receptor B2 (EPHB2) (AA 261-465) antibodyEPHB2 Reactivity: Human ELISA, IHC, IF Host: Rabbit Polyclonal unconjugated
anti-EPH Receptor B2 (EPHB2) (C-Term) antibodyEPHB2 Reactivity: Human, Mouse, Rat WB, ELISA, IHC, IF, ICC Host: Rabbit Polyclonal unconjugated
anti-EPH Receptor B2 (EPHB2) (pTyr298) antibodyEPHB2 Reactivity: Chicken WB Host: Rabbit Polyclonal unconjugated
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- Application Notes
- IF: 1:10~50. WB: 1:1000. IHC-P: 1:10~50. IHC-P: 1:10~50
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Storage Comment
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
- Expiry Date
- 6 months
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- Target
- EPH Receptor B2 (EPHB2)
- Alternative Name
- EphB2 (EPHB2 Products)
- Background
- Ephrin receptors and their ligands, the ephrins, mediate numerous developmental processes, particularly in the nervous system. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Ephrin receptors make up the largest subgroup of the receptor tyrosine kinase (RTK) family. The ligand-activated form of EphB2, which belongs to the Tyr family of protein kinases, interacts with multiple proteins, including GTPase-activating protein (RASGAP) through its SH2 domain. It binds RASGAP through the juxtamembrane tyrosines residues, and also interacts with PRKCABP and GRIP1 This type I membrane protein is expressed in brain, heart, lung, kidney, placenta, pancreas, liver and skeletal muscle. It is preferentially expressed in fetal brain. This protein contains putatively 2 fibronectin type III domains and 1 sterile alpha motif (SAM) domain.
- Molecular Weight
- 117493
- Gene ID
- 2048
- NCBI Accession
- NP_004433, NP_059145
- UniProt
- P29323
- Pathways
- RTK Signaling, Regulation of long-term Neuronal Synaptic Plasticity, S100 Proteins
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