NR2F6 antibody (N-Term)
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- Target See all NR2F6 Antibodies
- NR2F6 (Nuclear Receptor Subfamily 2, Group F, Member 6 (NR2F6))
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Binding Specificity
- N-Term
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Reactivity
- Human, Rat, Mouse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This NR2F6 antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
- Specificity
- NR2F6 Antibody detects endogenous levels of total NR2F6.
- Predicted Reactivity
- Pig,Bovine,Sheep,Dog,Chicken,Xenopus
- Purification
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide derived from human NR2F6, corresponding to a region within N-terminal amino acids.
- Isotype
- IgG
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anti-Nuclear Receptor Subfamily 2, Group F, Member 6 (NR2F6) (N-Term) antibody
NR2F6 Reactivity: Human WB, ELISA, IHC, IF Host: Rabbit Polyclonal unconjugated
anti-Nuclear Receptor Subfamily 2, Group F, Member 6 (NR2F6) (C-Term) antibodyNR2F6 Reactivity: Human WB, IHC (p), ChIP Host: Rabbit Polyclonal unconjugated
anti-Nuclear Receptor Subfamily 2, Group F, Member 6 (NR2F6) (N-Term) antibodyNR2F6 Reactivity: Human, Rat, Mouse, Dog IHC, IHC (p) Host: Rabbit Polyclonal unconjugated
anti-Nuclear Receptor Subfamily 2, Group F, Member 6 (NR2F6) (N-Term) antibodyNR2F6 Reactivity: Human, Rat, Mouse, Dog, Cow, Guinea Pig WB, IHC Host: Rabbit Polyclonal unconjugated
anti-Nuclear Receptor Subfamily 2, Group F, Member 6 (NR2F6) (AA 6-194) antibodyNR2F6 Reactivity: Human ELISA, IHC Host: Rabbit Polyclonal unconjugated
anti-Nuclear Receptor Subfamily 2, Group F, Member 6 (NR2F6) antibodyNR2F6 Reactivity: Human WB, FACS Host: Mouse Monoclonal EM-51 unconjugated
anti-Nuclear Receptor Subfamily 2, Group F, Member 6 (NR2F6) (Ligand Binding Domain) antibodyNR2F6 Reactivity: Human, Rat, Mouse, Dog, Cow, Pig, Zebrafish (Danio rerio), Monkey, Bat, Hamster, Xenopus laevis IHC, IHC (p) Host: Rabbit Polyclonal unconjugated
anti-Nuclear Receptor Subfamily 2, Group F, Member 6 (NR2F6) (N-Term) antibodyNR2F6 Reactivity: Human, Monkey IHC, IHC (p) Host: Rabbit Polyclonal unconjugated
anti-Nuclear Receptor Subfamily 2, Group F, Member 6 (NR2F6) (N-Term) antibodyNR2F6 Reactivity: Human, Rat, Mouse, Dog, Cow, Pig WB, IHC, IF, IP, IC Host: Rabbit Polyclonal unconjugated
anti-Nuclear Receptor Subfamily 2, Group F, Member 6 (NR2F6) (AA 11-60) antibodyNR2F6 Reactivity: Human, Rat, Mouse WB, ELISA, IHC, IF Host: Rabbit Polyclonal unconjugated
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- Application Notes
- WB 1:500-1:1000, IHC: 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20 °C. Stable for 12 months from date of receipt.
- Expiry Date
- 12 months
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- Target
- NR2F6 (Nuclear Receptor Subfamily 2, Group F, Member 6 (NR2F6))
- Alternative Name
- NR2F6 (NR2F6 Products)
- Synonyms
- EAR-2 antibody, EAR2 antibody, ERBAL2 antibody, AV090102 antibody, COUP-TF3 antibody, Erbal2 antibody, COUP(II) antibody, NR2F6 antibody, couptf2 antibody, fc94g11 antibody, wu:fc94g11 antibody, zgc:77259 antibody, ear-2 antibody, ear2 antibody, erbal2 antibody, nr2f6l antibody, wu:fc72d04 antibody, zgc:77260 antibody, nuclear receptor subfamily 2 group F member 6 antibody, nuclear receptor subfamily 2, group F, member 6 antibody, nuclear receptor subfamily 2, group F, member 6a antibody, nuclear receptor subfamily 2 group F member 6 L homeolog antibody, nuclear receptor subfamily 2, group F, member 6b antibody, NR2F6 antibody, Nr2f6 antibody, nr2f6a antibody, nr2f6.L antibody, nr2f6 antibody, nr2f6b antibody
- Background
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Description: Transcription factor predominantly involved in transcriptional repression. Binds to promoter/enhancer response elements that contain the imperfect 5'-AGGTCA-3' direct or inverted repeats with various spacings which are also recognized by other nuclear hormone receptors. Involved in modulation of hormonal responses. Represses transcriptional activity of the lutropin-choriogonadotropic hormone receptor/LHCGR gene, the renin/REN gene and the oxytocin-neurophysin/OXT gene. Represses the triiodothyronine-dependent and -independent transcriptional activity of the thyroid hormone receptor gene in a cell type-specific manner. The corepressing function towards thyroid hormone receptor beta/THRB involves at least in part the inhibition of THRB binding to triiodothyronine response elements (TREs) by NR2F6. Inhibits NFATC transcription factor DNA binding and subsequently its transcriptional activity. Acts as transcriptional repressor of IL-17 expression in Th-17 differentiated CD4+ T cells and may be involved in induction and/or maintenance of peripheral immunological tolerance and autoimmunity. Involved in development of forebrain circadian clock, is required early in the development of the locus coeruleus (LC).
Gene: NR2F6
- Molecular Weight
- 42 kDa
- Gene ID
- 2063
- UniProt
- P10588
- Pathways
- Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Photoperiodism
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