SNRPN antibody (N-Term)
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- Target See all SNRPN Antibodies
- SNRPN (Small Nuclear Ribonucleoprotein Polypeptide N (SNRPN))
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Binding Specificity
- N-Term
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Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This SNRPN antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)
- Purification
- Antigen affinity
- Immunogen
- An amino acid sequence from the N-terminus of human SNRPN (FKAFDKHMNLILCDCDEF) was used as the immunogen for this SNRPN antibody (100% homologous in human, mouse and rat).
- Isotype
- IgG
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anti-Small Nuclear Ribonucleoprotein Polypeptide N (SNRPN) (AA 46-95) antibody
SNRPN Reactivity: Human, Mouse, Rat, Dog, Cow, Guinea Pig, Horse, Rabbit, Monkey, Pig WB Host: Rabbit Polyclonal unconjugated
anti-Small Nuclear Ribonucleoprotein Polypeptide N (SNRPN) (AA 31-48), (N-Term) antibodySNRPN Reactivity: Human, Rat WB, IHC (p), ICC Host: Rabbit Polyclonal unconjugated
anti-Small Nuclear Ribonucleoprotein Polypeptide N (SNRPN) (AA 1-240) antibodySNRPN Reactivity: Human WB Host: Mouse Polyclonal unconjugated
anti-Small Nuclear Ribonucleoprotein Polypeptide N (SNRPN) (AA 1-100) antibodySNRPN Reactivity: Human WB Host: Rabbit Polyclonal unconjugated
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- Application Notes
- The stated application concentrations are suggested starting amounts. Titration of the SNRPN antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL,IHC (Paraffin): 0.5-1 μg/mL,Immunocytochemistry: 0.5-1 μg/mL
- Restrictions
- For Research Use only
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- Buffer
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
- Storage
- -20 °C
- Storage Comment
- After reconstitution, the SNRPN antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
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- Target
- SNRPN (Small Nuclear Ribonucleoprotein Polypeptide N (SNRPN))
- Alternative Name
- SNRPN (SNRPN Products)
- Synonyms
- SNRB' antibody, SNRPB' antibody, Snrpn antibody, zgc:77315 antibody, HCERN3 antibody, PWCR antibody, RT-LI antibody, SM-D antibody, SMN antibody, SNRNP-N antibody, SNURF-SNRPN antibody, sm-N antibody, 2410045I01Rik antibody, Peg4 antibody, Pwcr1 antibody, FE 294 antibody, FE 294 psi antibody, FE294 antibody, FE294 psi antibody, SNURF antibody, SNRPN antibody, QflA-11237 antibody, QtrA-10022 antibody, Sm-N antibody, SmN antibody, snRNP-N antibody, small nuclear ribonucleoprotein polypeptide-like antibody, small nuclear ribonucleoprotein polypeptides B and B1 antibody, small nuclear ribonucleoprotein polypeptide N antibody, small nuclear ribonucleoprotein N antibody, small nuclear ribonucleoparticle-associated protein (snRNP) mRNA, clone Sm51 antibody, SNRPN upstream reading frame antibody, Small nuclear ribonucleoprotein-associated protein N antibody, SNRPL antibody, snrpb antibody, SNRPN antibody, Snrpn antibody, snrpn antibody, SNURF antibody
- Background
- Small Nuclear Ribonucleoprotein Polypeptide N, also called SMN, is a bicistronic imprinted gene that encodes 2 polypeptides, the SmN splicing factor, which is involved in RNA processing, and the SNRPN upstream reading frame (SNURF) polypeptide. The protein encoded by this gene is one polypeptide of a small nuclear ribonucleoprotein complex and belongs to the snRNP SMB/SMN family. SNRPN also encodes a long alternatively spliced transcript containing several small nucleolar RNAs(snoRNAs) and extends downstream to partially overlap the UBE3A gene in the antisense orientation. PWS arises from loss of function of genes in this region expressed exclusively from the paternal chromosome, suggesting that SNRPN may play a role in its etiology. The gene is mapped on 15q11.2. Analysis of maternal DNA and of SNRPN cDNA confirmed that the maternal allele is not expressed in fetal brain and heart. Deletions in the transcription unit of the imprinted gene occur in patients who have PWS or Angelman syndrome because of a parental imprint switch failure in this chromosomal domain.
- UniProt
- P63162
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