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SCARB1 antibody (AA 21-100)

SCARB1 Reactivity: Human, Rat, Mouse, Chicken WB, ELISA, FACS, IHC (p) Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN738936
  • Target See all SCARB1 Antibodies
    SCARB1 (Scavenger Receptor Class B, Member 1 (SCARB1))
    Binding Specificity
    • 11
    • 10
    • 5
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 21-100
    Reactivity
    • 51
    • 29
    • 28
    • 2
    • 2
    • 2
    • 2
    • 1
    Human, Rat, Mouse, Chicken
    Host
    • 51
    • 8
    • 2
    Rabbit
    Clonality
    • 41
    • 20
    Polyclonal
    Conjugate
    • 35
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This SCARB1 antibody is un-conjugated
    Application
    • 38
    • 18
    • 15
    • 10
    • 9
    • 8
    • 8
    • 6
    • 5
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Cross-Reactivity
    Chicken, Human, Mouse, Rat
    Predicted Reactivity
    Cow,Pig,Horse,Rabbit
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human CD36L1
    Isotype
    IgG
  • Application Notes
    WB 1:300-5000
    ELISA 1:500-1000
    FCM 1:20-100
    IHC-P 1:200-400
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Expiry Date
    12 months
  • Gabriel, Becher-Deichsel, Hlavaty, Mair, Walter: "The physiological expression of scavenger receptor SR-B1 in canine endometrial and placental epithelial cells and its potential involvement in pathogenesis of pyometra." in: Theriogenology, Vol. 85, Issue 9, pp. 1599-1609.e2, (2016) (PubMed).

    Pollard, Blesso, Zabalawi, Fulp, Gerelus, Zhu, Lyons, Nuradin, Francone, Li, Sahoo, Thomas, Sorci-Thomas et al.: "Procollagen C-endopeptidase Enhancer Protein 2 (PCPE2) Reduces Atherosclerosis in Mice by Enhancing Scavenger Receptor Class B1 (SR-BI)-mediated High-density Lipoprotein (HDL)-Cholesteryl Ester ..." in: The Journal of biological chemistry, Vol. 290, Issue 25, pp. 15496-511, (2015) (PubMed).

  • Target
    SCARB1 (Scavenger Receptor Class B, Member 1 (SCARB1))
    Alternative Name
    Scavenger receptor class B member 1 (SCARB1 Products)
    Synonyms
    cb1015 antibody, SCARB1 antibody, Scarb1 antibody, CD36L1 antibody, CLA-1 antibody, CLA1 antibody, HDLQTL6 antibody, SR-BI antibody, SRB1 antibody, AI120173 antibody, CD36 antibody, Cd36l1 antibody, Cla-1 antibody, Cla1 antibody, D5Ertd460e antibody, Hdlq1 antibody, Hlb398 antibody, SR-B1 antibody, SRBI antibody, Srb1 antibody, mSR-BI antibody, scavenger receptor class B, member 1 antibody, scavenger receptor class B member 1 antibody, scarb1 antibody, SCARB1 antibody, Scarb1 antibody, CpipJ_CPIJ014332 antibody, CpipJ_CPIJ019101 antibody
    Background

    Synonyms: CLA1, SRB1, CLA-1, SR-BI, CD36L1, HDLQTL6, Scavenger receptor class B member 1, CD36 and LIMPII analogous 1, CD36 antigen-like 1, Collagen type I receptor, thrombospondin receptor-like 1, CD36, SCARB1

    Background: Receptor for different ligands such as phospholipids, cholesterol ester, lipoproteins, phosphatidylserine and apoptotic cells. Probable receptor for HDL, located in particular region of the plasma membrane, called caveolae. Facilitates the flux of free and esterified cholesterol between the cell surface and extracellular donors and acceptors, such as HDL and to a lesser extent, apoB-containing lipoproteins and modified lipoproteins. Probably involved in the phagocytosis of apoptotic cells, via its phosphatidylserine binding activity. Receptor for hepatitis C virus glycoprotein E2. Binding between SCARB1 and E2 was found to be independent of the genotype of the viral isolate. Plays an important role in the uptake of HDL cholesteryl ester (By similarity).

    Gene ID
    949
    UniProt
    Q8WTV0
    Pathways
    Cellular Response to Molecule of Bacterial Origin, Hepatitis C, Lipid Metabolism, SARS-CoV-2 Protein Interactome
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