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STAT2 antibody (AA 151-250)

STAT2 Reactivity: Human, Rat, Mouse WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN738246
  • Target See all STAT2 Antibodies
    STAT2 (Signal Transducer and Activator of Transcription 2, 113kDa (STAT2))
    Binding Specificity
    • 19
    • 15
    • 14
    • 9
    • 8
    • 7
    • 7
    • 6
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 151-250
    Reactivity
    • 114
    • 43
    • 37
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Rat, Mouse
    Host
    • 118
    • 7
    • 1
    Rabbit
    Clonality
    • 108
    • 18
    Polyclonal
    Conjugate
    • 61
    • 10
    • 9
    • 8
    • 5
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    This STAT2 antibody is un-conjugated
    Application
    • 104
    • 59
    • 46
    • 27
    • 26
    • 20
    • 12
    • 7
    • 6
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Cross-Reactivity
    Human, Mouse, Rat
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human STAT2
    Isotype
    IgG
    Top Product
    Discover our top product STAT2 Primary Antibody
  • Application Notes
    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Expiry Date
    12 months
  • Target
    STAT2 (Signal Transducer and Activator of Transcription 2, 113kDa (STAT2))
    Alternative Name
    STAT2 (STAT2 Products)
    Synonyms
    wu:fj84d07 antibody, p113 antibody, stat2 antibody, 1600010G07Rik antibody, AW496480 antibody, ISGF-3 antibody, P113 antibody, STAT113 antibody, signal transducer and activator of transcription 2 antibody, AGAP000099-PA antibody, stat2 antibody, STAT2 antibody, Stat2 antibody
    Background

    Synonyms: P113, ISGF-3, STAT113, Signal transducer and activator of transcription 2, STAT2

    Background: Signal transducer and activator of transcription that mediates signaling by type I IFNs (IFN-alpha and IFN-beta). Following type I IFN binding to cell surface receptors, Jak kinases (TYK2 and JAK1) are activated, leading to tyrosine phosphorylation of STAT1 and STAT2. The phosphorylated STATs dimerize, associate with IRF9/ISGF3G to form a complex termed ISGF3 transcription factor, that enters the nucleus. ISGF3 binds to the IFN stimulated response element (ISRE) to activate the transcription of interferon stimulated genes, which drive the cell in an antiviral state.

    Gene ID
    6773
    UniProt
    P52630
    Pathways
    JAK-STAT Signaling, Hepatitis C, CXCR4-mediated Signaling Events
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