ESR2 antibody (C-Term)
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- Target See all ESR2 Antibodies
- ESR2 (Estrogen Receptor 2 (ESR2))
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Binding Specificity
- C-Term
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Reactivity
- Human, Mouse, Rat, Sheep, Pig, Horse, Monkey
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This ESR2 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS), Staining Methods (StM)
- Purification
- Purified by Protein A/G
- Immunogen
- C-terminus fragment of recombinant human estrogen receptor beta protein
- Clone
- ERb455
- Isotype
- IgG2a kappa
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anti-Estrogen Receptor 2 (ESR2) (N-Term) antibody
ESR2 Reactivity: Human, Rat WB, IHC Host: Rabbit Polyclonal unconjugated
anti-Estrogen Receptor 2 (ESR2) (C-Term) antibodyESR2 Reactivity: Human, Mouse, Rat, Sheep, Pig, Horse, Monkey WB, IF, FACS, IHC (p) Host: Mouse Monoclonal ERb455 unconjugated
anti-Estrogen Receptor 2 (ESR2) (AA 201-300) antibodyESR2 Reactivity: Human, Mouse, Rat, Sheep WB, ELISA, FACS, IHC (p), IF (cc), IF (p), IHC (fro) Host: Rabbit Polyclonal unconjugated
anti-Estrogen Receptor 2 (ESR2) (AA 46-530) antibodyESR2 Reactivity: Mouse WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated
anti-Estrogen Receptor 2 (ESR2) (AA 50-100) antibodyESR2 Reactivity: Human, Mouse, Rat WB, ELISA, FACS, IHC (p), IF (cc), IF (p), IHC (fro) Host: Rabbit Polyclonal unconjugated
anti-Estrogen Receptor 2 (ESR2) (pSer105) antibodyESR2 Reactivity: Human, Mouse, Rat WB, ELISA, IF, ICC Host: Rabbit Polyclonal unconjugated
anti-Estrogen Receptor 2 (ESR2) (AA 211-240) antibodyESR2 Reactivity: Human, Mouse WB Host: Rabbit Polyclonal RB41114 unconjugated
anti-Estrogen Receptor 2 (ESR2) (AA 369-397) antibodyESR2 Reactivity: Human WB, FACS Host: Rabbit Polyclonal RB17812 unconjugated
anti-Estrogen Receptor 2 (ESR2) (AA 417-428) antibodyVerified ESR2 Reactivity: Human WB, ELISA, IF Host: Goat Polyclonal unconjugated
anti-Estrogen Receptor 2 (ESR2) (AA 22-121) antibodyESR2 Reactivity: Human WB, ELISA, IF Host: Mouse Monoclonal 3F3 unconjugated
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- Application Notes
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Positive Control: MCF-7 cells. Ovarian, Breast, Bladder, Gastric or Salivary carcinoma.
Known Application: Flow Cytometry (0.5-1 μg/million cells), Immunofluorescence (0.5-1 μg/mL), Western Blot (0.5-1 μg/mL), Immunohistochemistry (Formalin-fixed) (0.5-1 μg/mL for 30 minutes at RT) (Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.
- Restrictions
- For Research Use only
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- Concentration
- 200 μg/mL
- Buffer
- 10 mM PBS with 0.05 % BSA & 0.05 % azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C,-80 °C
- Storage Comment
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Expiry Date
- 24 months
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- Target
- ESR2 (Estrogen Receptor 2 (ESR2))
- Alternative Name
- ESR2 (ESR2 Products)
- Synonyms
- ER-BETA antibody, ESR-BETA antibody, ESRB antibody, ESTRB antibody, Erb antibody, NR3A2 antibody, ER[b]1 antibody, zfER-beta1 antibody, zfER[b]1 antibody, erb2 antibody, CERB antibody, ERB antibody, erb antibody, esrb antibody, estrb antibody, nr3a2 antibody, ERbeta antibody, er-beta antibody, esr-beta antibody, ESR2 antibody, ERBETA antibody, er antibody, ER-beta antibody, ER[b] antibody, Estrb antibody, ER[b]2 antibody, ER[b]a antibody, zfER[b]2 antibody, zfER-beta2 antibody, Erb2 antibody, esr2 antibody, erbeta antibody, Esr2 antibody, ERBeta2 antibody, estrogen receptor 2 antibody, estrogen receptor 2b antibody, estrogen receptor beta 2 antibody, estrogen receptor 2 (beta) antibody, estrogen receptor 2a antibody, estrogen receptor beta antibody, ESR2 antibody, esr2b antibody, erb2 antibody, esr2 antibody, Esr2 antibody, esr2a antibody, erbeta antibody
- Background
- Estrogen receptors (ER) are members of the steroid/thyroid hormone receptor superfamily of ligand-activated transcription factors. Estrogen receptors, including ER-alpha and ER-beta, contain DNA binding and ligand binding domains and are critically involved in regulating the normal function of reproductive tissues. They are located in the nucleus, though some estrogen receptors associate with the cell surface membrane and can be rapidly activated by exposure of cells to estrogen. ER-alpha and ER-beta are differentially activated by various ligands. Receptor-ligand interactions trigger a cascade of events, including dissociation from heat shock proteins, receptor dimerization, phosphorylation and the association of the hormone activated receptor with specific regulatory elements in target genes. Evidence suggests that ER-alpha and ER-beta may be regulated by distinct mechanisms even though they share many functional characteristics.
- Molecular Weight
- 53-59kDa
- Gene ID
- 2100
- UniProt
- Q92731
- Pathways
- Nuclear Receptor Transcription Pathway, EGFR Signaling Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling
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