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TCF7 antibody

TCF7 Reactivity: Mouse, Rat IHC, IF Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7075952
  • Target See all TCF7 Antibodies
    TCF7 (Transcription Factor 7 (T-Cell Specific, HMG-Box) (TCF7))
    Reactivity
    • 55
    • 39
    • 17
    • 7
    • 6
    • 6
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Mouse, Rat
    Host
    • 51
    • 4
    • 2
    Rabbit
    Clonality
    • 51
    • 6
    Polyclonal
    Conjugate
    • 36
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    This TCF7 antibody is un-conjugated
    Application
    • 41
    • 18
    • 14
    • 5
    • 3
    • 3
    • 2
    • 1
    Immunohistochemistry (IHC), Immunofluorescence (IF)
    Cross-Reactivity
    Rat
    Purification
    Affinity purification
    Immunogen
    Recombinant protein corresponding to Mouse TCF7
  • Application Notes
    IHC/IF (M,R) 1:600-1:1200/1:600-1:1200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS, pH 7.4, 0.02 % sodium azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
  • Target
    TCF7 (Transcription Factor 7 (T-Cell Specific, HMG-Box) (TCF7))
    Alternative Name
    TCF7 (TCF7 Products)
    Synonyms
    TCF-1 antibody, AI465550 antibody, Tcf1 antibody, Xtcf-1 antibody, Xtcf1 antibody, tcf-1 antibody, tcf1 antibody, tcf7 antibody, transcription factor 7 antibody, transcription factor 7, T cell specific antibody, transcription factor 7 S homeolog antibody, TCF7 antibody, Tcf7 antibody, tcf7 antibody, tcf7.S antibody
    Background
    TCF7 (transcriptional factor 7) is a transcriptional activator involved in T-cell lymphocyte differentiation. Necessary for the survival of CD4+ and CD8+ immature thymocytes. Isoforms for TCF7 lacking the N-terminal CTNNB1 binding domain cannot fulfill this role. TCF7 binds to the T-lymphocyte-specific enhancer element (5'-WWCAAAG-3') found in the promoter of the CD3E gene. It may also act as feedback transcriptional repressor of CTNNB1 and TCF7L2 target genes. TLE1, TLE2, TLE3, and TLE4 repress transactivation mediated by TCF7 and CTNNB1.
    Gene ID
    21414
    NCBI Accession
    NP_001300910
    UniProt
    Q00417
    Pathways
    WNT Signaling
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