CCM2 antibody
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- Target See all CCM2 Antibodies
- CCM2 (Cerebral Cavernous Malformation 2 (CCM2))
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Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This CCM2 antibody is un-conjugated
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Application
- Immunohistochemistry (IHC)
- Characteristics
- Polyclonal Antibody
- Purification
- Affinity purification
- Immunogen
- Recombinant fusion protein of human CCM2 (NP_113631.1).
- Isotype
- IgG
- Top Product
- Discover our top product CCM2 Primary Antibody
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anti-Cerebral Cavernous Malformation 2 (CCM2) (Internal Region) antibody
Verified CCM2 Reactivity: Human, Rat WB, IF, ELISA, FACS Host: Goat Polyclonal unconjugated
anti-Cerebral Cavernous Malformation 2 (CCM2) (AA 1-300) antibodyCCM2 Reactivity: Human WB, IHC Host: Rabbit Polyclonal unconjugated
anti-Cerebral Cavernous Malformation 2 (CCM2) (AA 1-444) antibodyCCM2 Reactivity: Human WB Host: Mouse Polyclonal unconjugated
anti-Cerebral Cavernous Malformation 2 (CCM2) (AA 1-300) antibodyCCM2 Reactivity: Human IHC, ELISA Host: Rabbit Polyclonal unconjugated
anti-Cerebral Cavernous Malformation 2 (CCM2) (AA 2-100) antibodyCCM2 Reactivity: Human WB, ELISA Host: Mouse Polyclonal unconjugated
anti-Cerebral Cavernous Malformation 2 (CCM2) (AA 1-444) antibodyCCM2 Reactivity: Human WB Host: Rabbit Polyclonal unconjugated
anti-Cerebral Cavernous Malformation 2 (CCM2) antibodyCCM2 Reactivity: Human, Mouse, Rat WB, IHC Host: Rabbit Polyclonal unconjugated
anti-Cerebral Cavernous Malformation 2 (CCM2) (AA 1-444), (N-Term) antibodyCCM2 Reactivity: Human WB, IF Host: Rabbit Polyclonal unconjugated
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- Application Notes
- IHC 1:50-1:200
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- CCM2 (Cerebral Cavernous Malformation 2 (CCM2))
- Alternative Name
- CCM2 (CCM2 Products)
- Synonyms
- C7orf22 antibody, OSM antibody, malcavernin antibody, CCM2 antibody, BC029157 antibody, TUF2 antibody, vtn antibody, zgc:110233 antibody, CCM2 scaffolding protein antibody, cerebral cavernous malformation 2 antibody, malcavernin antibody, CCM2 antibody, Ccm2 antibody, LOC100304744 antibody, ccm2 antibody
- Background
- This gene encodes a scaffold protein that functions in the stress-activated p38 Mitogen-activated protein kinase (MAPK) signaling cascade. The protein interacts with SMAD specific E3 ubiquitin protein ligase 1 (also known as SMURF1) via a phosphotyrosine binding domain to promote RhoA degradation. The protein is required for normal cytoskeletal structure, cell-cell interactions, and lumen formation in endothelial cells. Mutations in this gene result in cerebral cavernous malformations. Multiple transcript variants encoding different isoforms have been found for this gene.
- Gene ID
- 83605
- UniProt
- Q9BSQ5
- Pathways
- Cell-Cell Junction Organization
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