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Thrombopoietin antibody (AA 22-259)

Name: Thrombopoietin antibody (AA 22-259)
SKU: ABIN5518876
Price: 370 USD
Availability: InStock

THPO Reactivity: Rat, Mouse WB, ELISA, IHC (p) Host: Rabbit Polyclonal unconjugated

Western blot analysis of Thrombopoietin using anti-Thrombopoietin antibody .

IHC analysis of Thrombopoietin using anti- Thrombopoietin antibody .

IHC

6 images

Catalog No. ABIN5518876

Datasheet as PDF

Target See all Thrombopoietin (THPO) Antibodies

Thrombopoietin (THPO)
Binding Specificity
6

4

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1
AA 22-259
Reactivity
43

10

10

2

1

1

1
Rat, Mouse
Host
37

10

6

5
Rabbit
Compatible Secondaries
Clonality
49

9
Polyclonal
Conjugate
41

7

3

1

1

1

1

1

1

1
This Thrombopoietin antibody is un-conjugated
Application
44

26

6

5

4

4

3

2

2

2

1

1

1

1

1
Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purpose

Rabbit IgG polyclonal antibody for Thrombopoietin(Thpo) detection. Tested with WB, IHC-P, ELISA in Mouse,Rat.

Cross-Reactivity (Details)

No cross reactivity with other proteins.

Characteristics

Rabbit IgG polyclonal antibody for Thrombopoietin(Thpo) detection. Tested with WB, IHC-P, ELISA in Mouse,Rat.
Gene Name: thrombopoietin
Protein Name: Thrombopoietin

Purification

Immunogen affinity purified.

Immunogen

E. coli-derived mouse Thrombopoietin recombinant protein (Position: S22-H259). Mouse Thrombopoietin shares 79.3% and 92.9% amino acid (aa) sequence identity with human and rat Thrombopoietin, respectively.

Isotype

IgG
anti-Thrombopoietin (THPO) (AA 22-349) antibody
THPO Reactivity: Human WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated

anti-Thrombopoietin (THPO) antibody
THPO Reactivity: Human WB, ELISA, FACS Host: Mouse Monoclonal 1B11 unconjugated

anti-Thrombopoietin (THPO) (AA 25-298) antibody
THPO Reactivity: Human WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated

anti-Thrombopoietin (THPO) (AA 21-120) antibody
THPO Reactivity: Human, Rat, Mouse WB, ELISA, ICC, IHC (p), IF (cc), IF (p), IHC (fro) Host: Rabbit Polyclonal unconjugated

anti-Thrombopoietin (THPO) (AA 307-337) antibody
THPO Reactivity: Human WB Host: Rabbit Polyclonal unconjugated

anti-Thrombopoietin (THPO) (AA 24-266) antibody
THPO Reactivity: Rat WB, IHC, ICC Host: Rabbit Polyclonal unconjugated

anti-Thrombopoietin (THPO) antibody
THPO Reactivity: Human WB, EIA Host: Mouse Monoclonal 1B11 unconjugated

anti-Thrombopoietin (THPO) (Internal Region) antibody
THPO Reactivity: Human WB, ELISA Host: Rabbit Polyclonal unconjugated

anti-Thrombopoietin (THPO) (AA 22-194) antibody
THPO Reactivity: Rat WB, ELISA Host: Rabbit Polyclonal unconjugated

anti-Thrombopoietin (THPO) (AA 300-329), (C-Term) antibody
THPO Reactivity: Human WB Host: Rabbit Polyclonal RB14599 unconjugated

Application Notes

WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Mouse
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Mouse, Rat, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
ELISA: Concentration: 0.1-0.5 μg/mL, Tested Species: Mouse

Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.

Comment

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

Restrictions

For Research Use only
Format

Lyophilized

Reconstitution

Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration

500 μg/mL

Buffer

Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Preservative

Sodium azide

Precaution of Use

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage

4 °C,-20 °C

Storage Comment

At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
Target

Thrombopoietin (THPO)

Alternative Name

Thpo (THPO Products)

Synonyms

MGDF antibody, MKCSF antibody, ML antibody, MPLLG antibody, THCYT1 antibody, TPO antibody, Mgdf antibody, Ml antibody, Mpllg antibody, Tpo antibody, Tpo1 antibody, Tpo2 antibody, Tpo3 antibody, Tpo4 antibody, tpo antibody, LOC100231762 antibody, thrombopoietin antibody, THPO antibody, Thpo antibody, thpo antibody

Background

Thrombopoietin (THPO), also known as megakaryocyte growth and development factor (MGDF), is a protein that in humans is encoded by the THPO gene. Megakaryocytopoiesis is the cellular development process that leads to platelet production. The main functional protein encoded by this gene is a humoral growth factor that is necessary for megakaryocyte proliferation and maturation, as well as for thrombopoiesis. This protein is the ligand for MLP/C_MPL, the product of myeloproliferative leukemia virus oncogene. Mutations in this gene are the cause of thrombocythemia 1. Alternative promoter usage and differential splicing result in multiple transcript variants differing in the 5' UTR and/or coding region. Multiple AUG codons upstream of the main open reading frame (ORF) have been identified, and these upstream AUGs inhibit translation of the main ORF at different extent.

Synonyms: C mpl ligand | MGDF | MKCSF | ML | MPL ligand | MPLLG | THCYT1 | THPO | Thrombopoietin | TPO | P40225

Gene ID

21832

UniProt

P40226

Pathways

JAK-STAT Signaling, Hormone Activity