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THRB antibody

THRB Reactivity: Human, Mouse, Rat WB, IF Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7258710
  • Target See all THRB Antibodies
    THRB (Thyroid Hormone Receptor, beta (THRB))
    Reactivity
    • 52
    • 32
    • 31
    • 6
    • 5
    • 5
    • 5
    • 4
    • 4
    • 4
    • 3
    • 3
    • 1
    Human, Mouse, Rat
    Host
    • 50
    • 2
    • 2
    Rabbit
    Clonality
    • 52
    • 2
    Polyclonal
    Conjugate
    • 35
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This THRB antibody is un-conjugated
    Application
    • 50
    • 22
    • 15
    • 13
    • 13
    • 12
    • 7
    • 4
    • 4
    • 4
    • 3
    • 2
    Western Blotting (WB), Immunofluorescence (IF)
    Characteristics
    Polyclonal Antibody
    Purification
    Affinity purification
    Immunogen
    Recombinant fusion protein of human THRB (NP_000452.2).
    Isotype
    IgG
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    Discover our top product THRB Primary Antibody
  • Application Notes
    WB 1:500-1:2000 IF 1:50-1:200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    THRB (Thyroid Hormone Receptor, beta (THRB))
    Alternative Name
    THRB (THRB Products)
    Synonyms
    C-ERBA-2 antibody, C-ERBA-BETA antibody, ERBA2 antibody, GRTH antibody, NR1A2 antibody, PRTH antibody, THR1 antibody, THRB1 antibody, THRB2 antibody, Nr1a2 antibody, T3R[b] antibody, T3Rbeta antibody, Thrb1 antibody, Thrb2 antibody, c-erbAbeta antibody, TR-beta antibody, TR[b]1 antibody, fj24f03 antibody, trb antibody, wu:fj24f03 antibody, CTR BETA 2 antibody, TR-BETA antibody, LOC734147 antibody, thrb antibody, THRB antibody, C-erba-beta antibody, RATT3REC antibody, T3rec antibody, TRbeta antibody, THR antibody, TRbeta1 antibody, thyroid hormone receptor beta antibody, thyroid hormone receptor, beta antibody, thyroid hormone receptor, beta S homeolog antibody, thyroid hormone receptor, beta L homeolog antibody, THRB antibody, Thrb antibody, thrb antibody, thrb.S antibody, thrb.L antibody
    Background
    The protein encoded by this gene is a nuclear hormone receptor for triiodothyronine. It is one of the several receptors for thyroid hormone, and has been shown to mediate the biological activities of thyroid hormone. Knockout studies in mice suggest that the different receptors, while having certain extent of redundancy, may mediate different functions of thyroid hormone. Mutations in this gene are known to be a cause of generalized thyroid hormone resistance (GTHR), a syndrome characterized by goiter and high levels of circulating thyroid hormone (T3-T4), with normal or slightly elevated thyroid stimulating hormone (TSH). Several alternatively spliced transcript variants encoding the same protein have been observed for this gene.
    Molecular Weight

    Observed_MW: 53 kDa

    Calculated_MW: 52 kDa/54 kDa

    Gene ID
    7068
    UniProt
    P10828
    Pathways
    Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Sensory Perception of Sound
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