Phone:
+1 877 302 8632
Fax:
+1 888 205 9894 (Toll-free)
E-Mail:
orders@antibodies-online.com

Recombinant NKX2-1 antibody

NKX2-1 Reactivity: Human, Mouse, Rat IHC, StM Host: Rabbit Monoclonal NX2-1-1855R unconjugated Recombinant Antibody
Catalog No. ABIN6940746
  • Target See all NKX2-1 Antibodies
    NKX2-1 (NK2 Homeobox 1 (NKX2-1))
    Antibody Type
    Recombinant Antibody
    Reactivity
    • 81
    • 36
    • 36
    • 1
    • 1
    • 1
    • 1
    Human, Mouse, Rat
    Host
    • 53
    • 29
    Rabbit
    Clonality
    • 42
    • 40
    Monoclonal
    Conjugate
    • 41
    • 7
    • 4
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This NKX2-1 antibody is un-conjugated
    Application
    • 45
    • 37
    • 30
    • 27
    • 20
    • 12
    • 12
    • 3
    • 2
    • 2
    • 2
    • 1
    Immunohistochemistry (IHC), Staining Methods (StM)
    Specificity
    Recognizes a protein of 40 kDa, identified as Thyroid transcription factor-1 (TTF-1). TTF-1 is a member of the NKx2 family of homeodomain transcription factors. It is expressed in epithelial cells of the thyroid gland and the lung. Nuclei from liver, stomach, pancreas, small intestine, colon, kidney, breast, skin, testes, pituitary, prostate, and adrenal glands are unreactive. Anti-TTF-1 is useful in differentiating primary adenocarcinoma of the lung from metastatic carcinomas originating in the breast, mediastinal germ cell tumors, and malignant mesothelioma. It can also be used to differentiate small cell lung carcinoma from lymphoid infiltrates.Loss of TTF-1 expression in non-small cell lung carcinoma has been associated with aggressive behavior of such neoplasms. TTF-1 reactivity is also seen in thyroid malignancies.
    Purification
    Purified by Protein A/G
    Immunogen
    Recombinant human full-length TTF-1 protein
    Clone
    NX2-1-1855R
    Isotype
    IgG
    Top Product
    Discover our top product NKX2-1 Primary Antibody
  • Application Notes

    Positive Control: MAD109, MLE-15, H441-4 or H345 cells. Normal thyroid or lung.

    Known Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.

    Restrictions
    For Research Use only
  • Concentration
    200 μg/mL
    Buffer
    10 mM PBS with 0.05 % BSA & 0.05 % azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-80 °C
    Storage Comment
    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
    Expiry Date
    24 months
  • Target
    NKX2-1 (NK2 Homeobox 1 (NKX2-1))
    Alternative Name
    NKX2-1 (NKX2-1 Products)
    Synonyms
    BCH antibody, BHC antibody, NK-2 antibody, NKX2.1 antibody, NKX2A antibody, TEBP antibody, TITF1 antibody, TTF-1 antibody, TTF1 antibody, titf1-A antibody, Xnkx-2.1 antibody, NKX2-1 antibody, LOC100227803 antibody, AV026640 antibody, Nkx2.1 antibody, T/EBP antibody, Titf1 antibody, Ttf-1 antibody, nk2.1a antibody, nkx2.1 antibody, nkx2.4a antibody, titf1 antibody, titf1a antibody, NK2 homeobox 1 antibody, NK2 homeobox 1 L homeolog antibody, NK2 homeobox 4b antibody, NKX2-1 antibody, nkx2-1.L antibody, Nkx2-1 antibody, nkx2.4b antibody
    Molecular Weight
    40kDa
    Gene ID
    7080
    UniProt
    P43699
    Pathways
    Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Systemic Arterial Blood Pressure by Hormones, Cellular Glucan Metabolic Process, Feeding Behaviour
You are here:
Support