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Fatty Acid Synthase antibody (AA 1-439)

FASN Reactivity: Human WB, ELISA, IP, IF, IHC (p) Host: Mouse Monoclonal 3F2-1F3 unconjugated
Catalog No. ABIN560848
  • Target See all Fatty Acid Synthase (FASN) Antibodies
    Fatty Acid Synthase (FASN)
    Binding Specificity
    • 15
    • 6
    • 5
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-439
    Reactivity
    • 72
    • 40
    • 34
    • 16
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 58
    • 18
    • 2
    Mouse
    Clonality
    • 53
    • 25
    Monoclonal
    Conjugate
    • 53
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This Fatty Acid Synthase antibody is un-conjugated
    Application
    • 62
    • 23
    • 21
    • 19
    • 19
    • 15
    • 14
    • 14
    • 13
    • 5
    • 4
    • 3
    • 2
    • 1
    Western Blotting (WB), ELISA, Immunoprecipitation (IP), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Purpose
    Mouse monoclonal antibody raised against a full length recombinant FASN.
    Sequence
    MSTNDTIVSG TLPQRMASCL EVLDLFLNQP HMVLSSFVLA EKAAAYRDRD SQRDLVEAVA HILGIRDLAA VNLDSSLADL GLDSLMSVEV RQTLERELNL VLSVREVRQL TLRKLQELSS KADEASELAC PTPKEDGLAQ QQTQLNLRSL LVNPEGPTLM RLNSVQSSER PLFLVHPIEG STTVFHSLAS GLSIPTYGLQ CTRAAPLDSI HSLAAYYIDC IRQVQPEGPY RVAGYSYGAC VAFEMCSQLQ AQQSPAPTHN SLFLFDGSPT YVLAYTQSYR AKLTPGCEAE AETEAICFFV QQFTDMEHNR VLEALLPLKG LEERVAAAVD LIIKSHQGLD RQELSFAARS FYYKLRAAEQ YTPKAKYHGN VMLLRAKTGG AYGEDLGADY NLSQVCDGKV SVHVIEGDHR TLLEGSGLES IISIIHSSLA EPRVSVREG
    Cross-Reactivity
    Human
    Characteristics
    Antibody Reactive Against Recombinant Protein.
    Immunogen
    FASN (AAH07909, 1 a.a. ~ 439 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
    Clone
    3F2-1F3
    Isotype
    IgG1
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Buffer
    In 1x PBS, pH 7.4
    Handling Advice
    Aliquot to avoid repeated freezing and thawing.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Meller, Bicker, Montani, Ikenberg, Rostamzadeh, Sailer, Wild, Dietrich, Uhl, Sulser, Moch, Gorr, Stephan, Jung, Hankeln, Kristiansen: "Myoglobin expression in prostate cancer is correlated to androgen receptor expression and markers of tumor hypoxia." in: Virchows Archiv : an international journal of pathology, Vol. 465, Issue 4, pp. 419-27, (2014) (PubMed).

    Gorr, Wichmann, Pilarsky, Theurillat, Fabrizius, Laufs, Bauer, Koslowski, Horn, Burmester, Hankeln, Kristiansen: "Old proteins - new locations: myoglobin, haemoglobin, neuroglobin and cytoglobin in solid tumours and cancer cells." in: Acta physiologica (Oxford, England), Vol. 202, Issue 3, pp. 563-81, (2011) (PubMed).

    Kristiansen, Rose, Geisler, Fritzsche, Gerhardt, Lüke, Ladhoff, Knüchel, Dietel, Moch, Varga, Theurillat, Gorr, Dahl: "Endogenous myoglobin in human breast cancer is a hallmark of luminal cancer phenotype." in: British journal of cancer, Vol. 102, Issue 12, pp. 1736-45, (2010) (PubMed).

  • Target
    Fatty Acid Synthase (FASN)
    Alternative Name
    FASN (FASN Products)
    Background
    Full Gene Name: fatty acid synthase
    Synonyms: FAS,MGC14367,MGC15706,OA-519,SDR27X1
    Gene ID
    2194
    Pathways
    AMPK Signaling
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