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TWEAK antibody (N-Term)

TNFSF12 Reactivity: Human, Mouse, Rat WB, ELISA, IHC, IF, ICC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6265650
  • Target See all TWEAK (TNFSF12) Antibodies
    TWEAK (TNFSF12) (Tumor Necrosis Factor (Ligand) Superfamily, Member 12 (TNFSF12))
    Binding Specificity
    • 6
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivity
    • 61
    • 24
    • 14
    • 4
    • 1
    • 1
    • 1
    Human, Mouse, Rat
    Host
    • 44
    • 11
    • 10
    • 2
    Rabbit
    Clonality
    • 55
    • 11
    • 1
    Polyclonal
    Conjugate
    • 38
    • 10
    • 5
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This TWEAK antibody is un-conjugated
    Application
    • 39
    • 25
    • 16
    • 13
    • 6
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
    Specificity
    TWEAK Antibody detects endogenous levels of total TWEAK.
    Predicted Reactivity
    Pig
    Purification
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogen
    A synthesized peptide derived from human TWEAK, corresponding to a region within N-terminal amino acids.
    Isotype
    IgG
    Top Product
    Discover our top product TNFSF12 Primary Antibody
  • Application Notes
    WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20 °C. Stable for 12 months from date of receipt.
    Expiry Date
    12 months
  • Target
    TWEAK (TNFSF12) (Tumor Necrosis Factor (Ligand) Superfamily, Member 12 (TNFSF12))
    Alternative Name
    TNFSF12 (TNFSF12 Products)
    Synonyms
    APO3L antibody, DR3LG antibody, TWEAK antibody, Apo3l antibody, Dr3l antibody, Dr3lg antibody, Tweak antibody, TNF superfamily member 12 antibody, tumor necrosis factor (ligand) superfamily, member 12 antibody, TNFSF12 antibody, Tnfsf12 antibody
    Background

    Description: Binds to FN14 and possibly also to TNRFSF12/APO3. Weak inducer of apoptosis in some cell types. Mediates NF-kappa-B activation. Promotes angiogenesis and the proliferation of endothelial cells. Also involved in induction of inflammatory cytokines. Promotes IL8 secretion.

    Gene: TNFSF12

    Molecular Weight
    27kDa
    Gene ID
    407977, 8742
    UniProt
    O43508
    Pathways
    Apoptosis
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