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GRP94 antibody (C-Term)

HSP90B1 Reactivity: Human, Mouse, Rat WB, IF, IP, ICC, IHC (p) Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2855586
  • Target See all GRP94 (HSP90B1) Antibodies
    GRP94 (HSP90B1) (Heat Shock Protein 90kDa beta (Grp94), Member 1 (HSP90B1))
    Binding Specificity
    • 21
    • 18
    • 16
    • 7
    • 7
    • 7
    • 7
    • 7
    • 6
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivity
    • 132
    • 85
    • 54
    • 40
    • 35
    • 31
    • 30
    • 30
    • 28
    • 28
    • 26
    • 26
    • 25
    • 17
    • 10
    • 2
    • 2
    • 1
    • 1
    Human, Mouse, Rat
    Host
    • 92
    • 40
    • 24
    • 2
    • 1
    Rabbit
    Clonality
    • 93
    • 66
    Polyclonal
    Conjugate
    • 69
    • 12
    • 11
    • 11
    • 10
    • 8
    • 4
    • 4
    • 4
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This GRP94 antibody is un-conjugated
    Application
    • 151
    • 83
    • 68
    • 63
    • 49
    • 45
    • 38
    • 20
    • 13
    • 13
    • 12
    • 11
    • 4
    • 4
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunoprecipitation (IP), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Cross-Reactivity
    Dog (Canine), Monkey, Pig (Porcine)
    Cross-Reactivity (Details)
    Dog (95 %), Monkey (98 %), Pig (95 %)
    Characteristics
    Rabbit Polyclonal antibody to GRP94 (heat shock protein 90 kDa beta (Grp94), member 1)
    GRP94 antibody
    Purification
    Purified by antigen-affinity chromatography.
    Immunogen
    Recombinant protein encompassing a sequence within the C-terminus region of human GRP94. The exact sequence is proprietary.
    Isotype
    IgG
    Top Product
    Discover our top product HSP90B1 Primary Antibody
  • Application Notes
    Suggested dilution Reference ICC/IF 1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections) 1:100-1:1000* Immunoprecipitation 1:100-1:500* Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceICC/IF1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections)1:100-1:1000* Immunoprecipitation1:100-1:500* Western blot1:500-1:3000*
    Comment

    Positive Control: 293T , A431 , HeLa , HepG2 , NIH-3T3 , Mouse brain , PC-12 , Rat-2

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.
    Preservative
    Thimerosal (Merthiolate)
    Precaution of Use
    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Brzozowa-Zasada, Kurek, Piecuch, Wyrobiec: "The clinical and prognostic evaluation of GRP94 immunoexpression in Caucasian patients with colorectal adenocarcinoma." in: Przeglad gastroenterologiczny, Vol. 14, Issue 2, pp. 140-147, (2019) (PubMed).

  • Target
    GRP94 (HSP90B1) (Heat Shock Protein 90kDa beta (Grp94), Member 1 (HSP90B1))
    Alternative Name
    GRP94 (HSP90B1 Products)
    Synonyms
    ecgp antibody, gp96 antibody, tra1 antibody, grp94 antibody, DDBDRAFT_0206450 antibody, DDBDRAFT_0215015 antibody, DDB_0206450 antibody, DDB_0215015 antibody, TRA1 antibody, HSP90B1 antibody, ERp99 antibody, GRP94 antibody, TA-3 antibody, Targ2 antibody, Tra-1 antibody, Tra1 antibody, endoplasmin antibody, GP96 antibody, fb61d09 antibody, tra-1 antibody, wu:fb61d09 antibody, wu:fq25g01 antibody, Grp94 antibody, ECGP antibody, Gp96 antibody, ppk98 antibody, hsp108 antibody, heat shock protein 90kDa beta (Grp94), member 1 antibody, heat shock protein Hsp90 family protein antibody, 94 kD glucose-regulated protein antibody, heat shock protein 90 beta family member 1 antibody, heat shock protein 90, beta (Grp94), member 1 antibody, heat shock protein 90, beta (grp94), member 1 antibody, heat shock protein 90kDa beta family member 1 L homeolog antibody, hsp90b1 antibody, grp94 antibody, HSP90B1 antibody, Hsp90b1 antibody, hsp90b1.L antibody
    Background
    HSP90 proteins are highly conserved molecular chaperones that have key roles in signal transduction, protein folding, protein degradation, and morphologic evolution. HSP90 proteins normally associate with other cochaperones and play important roles in folding newly synthesized proteins or stabilizing and refolding denatured proteins after stress. HSP90B1 is an endoplasmic reticulum HSP90 protein. Other HSP90 proteins are found in cytosol (see HSP90AA1, MIM 140571) and mitochondria (TRAP1, MIM 606219) (Chen et al., 2005 [PubMed 16269234]).[supplied by OMIM]

    Cellular Localization: Endoplasmic reticulum lumen , Melanosome
    Molecular Weight
    92 kDa
    Gene ID
    7184
    Pathways
    Thyroid Hormone Synthesis, Activation of Innate immune Response, ER-Nucleus Signaling, Toll-Like Receptors Cascades
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