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FCAR antibody (AA 22-227)

FCAR Reactivity: Human WB, ELISA, FACS, IHC, ICC, Neut Host: Mouse Monoclonal 2F9E10 unconjugated
Catalog No. ABIN5684138
  • Target See all FCAR Antibodies
    FCAR (Fc Fragment of IgA, Receptor For (FCAR))
    Binding Specificity
    • 15
    • 8
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 22-227
    Reactivity
    • 61
    • 21
    • 9
    • 5
    • 3
    Human
    Host
    • 49
    • 17
    Mouse
    Clonality
    • 50
    • 15
    • 1
    Monoclonal
    Conjugate
    • 27
    • 6
    • 6
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This FCAR antibody is un-conjugated
    Application
    • 26
    • 23
    • 18
    • 13
    • 13
    • 9
    • 6
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Neutralization (Neut)
    Purification
    purified
    Immunogen
    Purified recombinant fragment of human CD89 (AA: extra 22-227) expressed in E. coli.
    Clone
    2F9E10
    Isotype
    IgG1
  • Application Notes
    ELISA: 1:10000, WB: 1:500 - 1:2000, ICC: N/A, FCM: 1:200 - 1:400, IHC: N/A
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified antibody in PBS with 0.05 % sodium azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C/-20 °C
    Storage Comment
    4°C, -20°C for long term storage
  • Target
    FCAR (Fc Fragment of IgA, Receptor For (FCAR))
    Alternative Name
    CD89 (FCAR Products)
    Synonyms
    CD89 antibody, Fc fragment of IgA receptor antibody, Fc fragment of IgA, receptor for antibody, FCAR antibody
    Background

    Description: This gene is a member of the immunoglobulin gene superfamily and encodes a receptor for the Fc region of IgA. The receptor is a transmembrane glycoprotein present on the surface of myeloid lineage cells such as neutrophils, monocytes, macrophages, and eosinophils, where it mediates immunologic responses to pathogens. It interacts with IgA-opsonized targets and triggers several immunologic defense processes, including phagocytosis, antibody-dependent cell-mediated cytotoxicity, and stimulation of the release of inflammatory mediators. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene.

    Aliases: FCAR, FcalphaRI, CTB-61M7.2

    Molecular Weight
    32.3 kDa
    Gene ID
    2204
    HGNC
    2204
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