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Protein Tob1 (TOB1) (AA 54-83), (N-Term) antibody

Name: Protein Tob1 (TOB1) (AA 54-83), (N-Term) antibody
SKU: ABIN652511
Price: 429 USD
Availability: InStock

TOB1 Reactivity: Human, Mouse WB, IHC (p), FACS Host: Rabbit Polyclonal RB19906 unconjugated

Western blot analysis of TOB1 Antibody (N-term) (ABIN652511 and ABIN2842342) in mouse liver tissue lysates (35 μg/lane).

TOB1 Antibody (N-term) (ABIN652511 and ABIN2842342) flow cytometric analysis of NCI- cells (bottom histogram) compared to a negative control cell (top histogram).

FACS

Formalin-fixed and paraffin-embedded human hepatocarcinoma reacted with TOB1 Antibody (N-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining.

IHC (p)

3 images

Catalog No. ABIN652511

Datasheet as PDF

Target See all Protein Tob1 (TOB1) Antibodies

Protein Tob1 (TOB1)
Binding Specificity
15

10

9

9

7

5

2

2

1

1

1

1

1

1
AA 54-83, N-Term
Reactivity
48

31

27

5

5

5

3

2

1

1

1

1

1
Human, Mouse
Host
62

2
Rabbit
Compatible Secondaries
Clonality
64
Polyclonal
Conjugate
22

6

5

4

3

3

3

3

3

3

2

2

1

1

1

1

1
Un-conjugated
Application
31

26

13

13

10

7

4

3

3

1

1
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Predicted Reactivity

Rat

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen

This TOB1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 54-83 amino acids from the N-terminal region of human TOB1.

Clone

RB19906

Isotype

Ig Fraction

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anti-Protein Tob1 (TOB1) (AA 42-175) antibody
TOB1 Reactivity: Human WB, ELISA, IHC, IF Host: Rabbit Polyclonal unconjugated

anti-Protein Tob1 (TOB1) (AA 1-345) antibody
TOB1 Reactivity: Human WB, IHC (p), IF Host: Mouse Polyclonal unconjugated

anti-Protein Tob1 (TOB1) (Ser164) antibody
TOB1 Reactivity: Human WB, ELISA, IHC Host: Rabbit Polyclonal unconjugated

anti-Protein Tob1 (TOB1) (pSer164) antibody
TOB1 Reactivity: Human WB, ELISA, IHC Host: Rabbit Polyclonal unconjugated

anti-Protein Tob1 (TOB1) antibody
TOB1 Reactivity: Human, Mouse WB, IHC, FACS Host: Rabbit Polyclonal unconjugated

anti-Protein Tob1 (TOB1) (AA 61-91), (N-Term) antibody
TOB1 Reactivity: Human, Mouse WB, IHC (p), FACS, EIA Host: Rabbit Polyclonal unconjugated

anti-Protein Tob1 (TOB1) (pSer164) antibody
TOB1 Reactivity: Human, Mouse, Rat WB, ELISA, IHC Host: Rabbit Polyclonal unconjugated

anti-Protein Tob1 (TOB1) (AA 173-222) antibody
TOB1 Reactivity: Mouse, Hamster WB Host: Rabbit Polyclonal unconjugated

anti-Protein Tob1 (TOB1) (AA 215-264) antibody
TOB1 Reactivity: Human, Mouse, Cow, Dog, Horse, Drosophila melanogaster, Monkey WB Host: Rabbit Polyclonal unconjugated

anti-Protein Tob1 (TOB1) (AA 130-179), (pSer164) antibody
TOB1 Reactivity: Human, Mouse, Rat WB, ELISA, IHC Host: Rabbit Polyclonal unconjugated

Application Notes

WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50

Restrictions

For Research Use only
Format

Liquid

Buffer

Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative

Sodium azide

Precaution of Use

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage

4 °C,-20 °C

Storage Comment

Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date

6 months
Target

Protein Tob1 (TOB1)

Alternative Name

TOB1 (TOB1 Products)

Synonyms

Tob antibody, Trob antibody, APRO5 antibody, APRO6 antibody, PIG49 antibody, TOB antibody, TROB antibody, TROB1 antibody, tob1 antibody, tob1l antibody, wu:fb54d02 antibody, wu:fb98h12 antibody, wu:fd15f10 antibody, zgc:65837 antibody, transducer of ErbB-2.1 antibody, transducer of ERBB2, 1 antibody, transducer of ERBB2, 1a antibody, transducer of ERBB2, 1 S homeolog antibody, transducer of ERBB2, 1b antibody, Tob1 antibody, TOB1 antibody, tob1a antibody, tob1.S antibody, tob1b antibody

Background

TOB1 is a member of the tob/btg1 family of anti-proliferative proteins that have the potential to regulate cell growth. When exogenously expressed, this protein supresses cell growth in tissue culture. The protein undergoes phophorylation by a serine/threonine kinase, 90 kDa ribosomal S6 kinase. Interactions of this protein with the v-erb-b2 erythroblastic leukemia viral oncogene homolog 2 gene product p185 interferes with growth suppression. This protein inhibits T cell proliferation and transcription of cytokines and cyclins. The protein interacts with both mothers against decapentaplegic Drosophila homolog 2 and 4 to enhance their DNA binding activity. This interaction inhibits interleukin 2 transcription in T cells.

Molecular Weight

38155

Gene ID

10140

NCBI Accession

NP_001230806, NP_001230814, NP_005740

UniProt

P50616