Ubiquitin B antibody (N-Term)
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- Target See all Ubiquitin B (UBB) Antibodies
- Ubiquitin B (UBB)
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Binding Specificity
- AA 25-57, N-Term
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Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This Ubiquitin B antibody is un-conjugated
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Application
- Western Blotting (WB)
- Predicted Reactivity
- B, E, D, Pr, Pig, Sh, C, Hs, Ha, X, Rb
- Purification
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- Immunogen
- This UBB(Ubiquitin) antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 25-57amino acids from the N-terminal region of human UBB(Ubiquitin).
- Clone
- RB49507
- Isotype
- Ig Fraction
- Top Product
- Discover our top product UBB Primary Antibody
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anti-Ubiquitin B (UBB) (AA 1-119) antibody
UBB Reactivity: Human WB, IHC, IF, FACS, StM Host: Mouse Monoclonal UBB-1748 unconjugated
anti-Ubiquitin B (UBB) antibodyUBB Reactivity: Human WB, ELISA, FACS Host: Mouse Monoclonal 3C12 unconjugated
anti-Ubiquitin B (UBB) (AA 1-119) antibodyUBB Reactivity: Human WB, ELISA, IHC, StM, Coat Host: Mouse Monoclonal UBB-2122 unconjugated
anti-Ubiquitin B (UBB) (C-Term) antibodyUBB Reactivity: Human WB, IF, IHC (p) Host: Rabbit Polyclonal unconjugated
anti-Ubiquitin B (UBB) (AA 1-76) antibodyUBB Reactivity: Human WB, ELISA, IHC (p) Host: Mouse Monoclonal 1F5 unconjugated
anti-Ubiquitin B (UBB) (AA 1-76) antibodyUBB Reactivity: Human WB, IHC Host: Rabbit Polyclonal unconjugated
anti-Ubiquitin B (UBB) (AA 77-152) antibodyUBB Reactivity: Human, Mouse, Rat WB, IHC (p) Host: Rabbit Polyclonal unconjugated
anti-Ubiquitin B (UBB) (AA 103-228) antibodyUBB Reactivity: Human ELISA, IHC Host: Rabbit Polyclonal unconjugated
anti-Ubiquitin B (UBB) (AA 1-119) antibodyUBB Reactivity: Human IHC, StM Host: Rabbit Monoclonal UBB-3143R unconjugated Recombinant Antibody
anti-Ubiquitin B (UBB) (N-Term) antibodyUBB Reactivity: Human WB, IHC (p) Host: Rabbit Polyclonal unconjugated
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- Application Notes
- WB: 1:1000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Expiry Date
- 6 months
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- Target
- Ubiquitin B (UBB)
- Alternative Name
- UBB(Ubiquitin) (UBB Products)
- Background
- Ubiquitin exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be involved in DNA repair, Lys-11-linked is involved in ERAD (endoplasmic reticulum-associated degradation) and in cell-cycle regulation, Lys-29-linked is involved in lysosomal degradation, Lys-33-linked is involved in kinase modification, Lys-48-linked is involved in protein degradation via the proteasome, Lys-63-linked is involved in endocytosis, DNA-damage responses as well as in signaling processes leading to activation of the transcription factor NF-kappa-B. Linear polymer chains formed via attachment by the initiator Met lead to cell signaling. Ubiquitin is usually conjugated to Lys residues of target proteins, however, in rare cases, conjugation to Cys or Ser residues has been observed. When polyubiquitin is free (unanchored-polyubiquitin), it also has distinct roles, such as in activation of protein kinases, and in signaling.
- Molecular Weight
- 25762
- UniProt
- P0CG47
- Pathways
- Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Mitotic G1-G1/S Phases, DNA Replication, Toll-Like Receptors Cascades, Synthesis of DNA, Autophagy, EGFR Downregulation, Ubiquitin Proteasome Pathway
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