UMPS antibody (C-Term)
(1 reference)-
- Target See all UMPS Antibodies
- UMPS (Uridine Monophosphate Synthetase (UMPS))
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Binding Specificity
- C-Term
- Reactivity
- Human, Mouse, Rat, Rabbit, Guinea Pig, Horse, Dog, Cow, Pig, Saccharomyces cerevisiae
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This UMPS antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (IHC)
- Sequence
- VGFISGSRVS MKPEFLHLTP GVQLEAGGDN LGQQYNSPQE VIGKRGSDII
- Predicted Reactivity
- Cow: 93%, Dog: 100%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 93%, Yeast: 75%
- Characteristics
- This is a rabbit polyclonal antibody against UMPS. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the C terminal region of human UMPS
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anti-Uridine Monophosphate Synthetase (UMPS) (AA 381-479) antibody
UMPS Reactivity: Human WB, ELISA, IF Host: Mouse Monoclonal 2F5 unconjugated
anti-Uridine Monophosphate Synthetase (UMPS) (AA 314-444) antibodyUMPS Reactivity: Human ELISA, IHC, IF Host: Rabbit Polyclonal unconjugated
anti-Uridine Monophosphate Synthetase (UMPS) (AA 311-481) antibodyUMPS Reactivity: Mouse WB, IHC, ICC Host: Rabbit Polyclonal unconjugated
anti-Uridine Monophosphate Synthetase (UMPS) antibodyUMPS Reactivity: Human, Mouse WB, ELISA, IHC Host: Rabbit Polyclonal unconjugated
anti-Uridine Monophosphate Synthetase (UMPS) (AA 1-480) antibodyUMPS Reactivity: Human WB Host: Rabbit Polyclonal unconjugated
anti-Uridine Monophosphate Synthetase (UMPS) (AA 1-480) antibodyUMPS Reactivity: Human WB Host: Mouse Polyclonal unconjugated
anti-Uridine Monophosphate Synthetase (UMPS) (AA 100-260) antibodyUMPS Reactivity: Human WB, IF Host: Rabbit Polyclonal unconjugated
anti-Uridine Monophosphate Synthetase (UMPS) (AA 351-450) antibodyUMPS Reactivity: Human, Cynomolgus, Rhesus Monkey WB, ELISA, IF (cc), IF (p), ICC, IHC (p), IHC (fro) Host: Rabbit Polyclonal unconjugated
anti-Uridine Monophosphate Synthetase (UMPS) (AA 30-70) antibodyUMPS Reactivity: Human WB Host: Rabbit Polyclonal RB47355 unconjugated
anti-Uridine Monophosphate Synthetase (UMPS) (AA 381-479) antibodyUMPS Reactivity: Human WB, ELISA Host: Mouse Polyclonal unconjugated
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 480 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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: "Effect of varicocelectomy on patients with unobstructive azoospermia and severe oligospermia." in: BJU international, Vol. 101, Issue 2, pp. 216-8, (2008) (PubMed).
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: "Effect of varicocelectomy on patients with unobstructive azoospermia and severe oligospermia." in: BJU international, Vol. 101, Issue 2, pp. 216-8, (2008) (PubMed).
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- Target
- UMPS (Uridine Monophosphate Synthetase (UMPS))
- Alternative Name
- UMPS (UMPS Products)
- Synonyms
- zgc:55702 antibody, zgc:55723 antibody, UMPS antibody, OPRT antibody, 1700095D23Rik antibody, AA408257 antibody, AL033308 antibody, BB164745 antibody, Orotidine 5'-phosphate decarboxylase antibody, uridine monophosphate synthetase antibody, uridine monophosphate synthetase L homeolog antibody, uridine 5'-monophosphate synthase antibody, umps-1 antibody, umps antibody, umps.L antibody, UMPS antibody, LOC100556619 antibody, Umps antibody
- Background
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OPRT (UMPS) is involved in early events of pancreatic and gallbladder carcinogenesis and invasion of hepatocellular carcinomas. Orotate phosphoribosyltransferase is involved in the invasion and metastasis of colorectal carcinoma. Determination of OPRT levels in gastric carcinoma tissue enables to predict the response to S-1-based neoadjuvant/adjuvant chemotherapy.
Alias Symbols: OPRT
Protein Interaction Partner: UBC, CALU, PLA2G12A, ZNF227, RPS29, PAXIP1, PSEN1, NOS3, APRT, A2M, CUL3, USP50, CDC42EP3, DLST,
Protein Size: 480 - Molecular Weight
- 52 kDa
- Gene ID
- 7372
- NCBI Accession
- NM_000373, NP_000364
- UniProt
- P11172
- Pathways
- Ribonucleoside Biosynthetic Process
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