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FGD1 antibody (AA 700-800)

FGD1 Reactivity: Human WB, IHC, IF Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7267284
  • Target See all FGD1 Antibodies
    FGD1 (FYVE, RhoGEF and PH Domain Containing 1 (FGD1))
    Binding Specificity
    • 3
    • 2
    • 1
    AA 700-800
    Reactivity
    • 7
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    Human
    Host
    • 7
    Rabbit
    Clonality
    • 7
    Polyclonal
    Conjugate
    • 7
    This FGD1 antibody is un-conjugated
    Application
    • 6
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
    Purpose
    FGD1 Rabbit pAb
    Sequence
    LLNSTNREDE DTPPNSPNVD LGKRAPTPIR EKEVTMCMRC QEPFNSITKR RHHCKACGHV VCGKCSEFRA RLVYDNNRSN RVCTDCYVAL HGVPGSSPAC S
    Cross-Reactivity
    Human, Mouse, Rat
    Characteristics
    Polyclonal Antibodies
    Purification
    Affinity purification
    Immunogen
    A synthetic peptide corresponding to a sequence within amino acids 700-800 of human FGD1 (NP_004454.2).
    Isotype
    IgG
  • Application Notes
    WB,1:500 - 1:2000,IHC,1:50 - 1:100,IF,1:50 - 1:100
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    FGD1 (FYVE, RhoGEF and PH Domain Containing 1 (FGD1))
    Alternative Name
    FGD1 (FGD1 Products)
    Synonyms
    AAS antibody, FGDY antibody, MRXS16 antibody, ZFYVE3 antibody, FYVE, RhoGEF and PH domain containing 1 antibody, FGD1 antibody, Fgd1 antibody, fgd1 antibody
    Background
    This gene encodes a protein that contains Dbl (DH) and pleckstrin (PH) homology domains and is similar to the Rho family of small GTP-binding proteins. The encoded protein specifically binds to the Rho family GTPase Cdc42Hs and can stimulate the GDP-GTP exchange of the isoprenylated form of Cdc42Hs. It also stimulates the mitogen activated protein kinase cascade leading to c-Jun kinase SAPK/JNK1 activation. Defects in this gene are the cause of faciogenital dysplasia and X-linked mental retardation, syndromatic 16.,FGD1,AAS,FGDY,MRXS16,ZFYVE3,FYVE,Signal Transduction,G protein signaling,G-Protein-Coupled Receptors(GPCR),Cell Biology & Developmental Biology,Cytoskeleton,Microfilaments,FGD1
    Molecular Weight
    106kDa
    Gene ID
    2245
    UniProt
    P98174
    Pathways
    Neurotrophin Signaling Pathway
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