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FGF2 antibody (AA 143-250)

Name: FGF2 antibody (AA 143-250)
SKU: ABIN726425
Price: 384.62 USD
Availability: InStock

FGF2 Reactivity: Human, Mouse, Rat, Rabbit, Sheep WB, ELISA, IHC (p), FACS, IF (cc), IF (p), IHC (fro) Host: Rabbit Polyclonal unconjugated

(a) Representative Masson staining images of the heart papillary muscle cross-sectional scan images, and infarct rate of the different groups.

Formalin-fixed and paraffin embedded: rat brain tissue labeled with Anti-bFGF Polyclonal Antibody, Unconjugated (ABIN726425) at 1:200, followed by conjugation to the secondary antibody and DAB staining

IHC

Formalin-fixed and paraffin embedded mouse kidney labeled with Anti-BFGF/FGF2 Polyclonal Antibody, Unconjugated (ABIN726425) followed by conjugation to the secondary antibody and DAB staining

IHC

Human HepG2 cells probed with Rabbit Anti-bFGF Polyclonal Antibody

FACS

Image provided by One World Lab validation program.

IF (cc)

Formalin-fixed and paraffin embedded: rat brain tissue labeled with Anti-bFGF Polyclonal Antibody, Unconjugated at 1:200, followed by conjugation to the secondary antibody and DAB staining

IHC (p)

Mouse spleen lysates probed with bFGF Polyclonal Antibody, Unconjugated at 1:300 dilution and 4˚C overnight incubation.

HepG2 lysates probed with bFGF Polyclonal Antibody, Unconjugated at 1:500 dilution and 4˚C overnight incubation.

(a) Representative images and bar graphs of the transmigrated cell number in the labeled and unlabeled endothelial progenitor cell (EPC) groups (x200).

9 images

(18 references)

Catalog No. ABIN726425

Datasheet as PDF

Target See all FGF2 Antibodies

FGF2 (Fibroblast Growth Factor 2 (Basic) (FGF2))
Binding Specificity
39

15

12

7

6

6

3

3

2

2

2

2

2

1

1

1

1

1
AA 143-250
Reactivity
128

56

53

20

17

16

5

3

3

2

2

1

1
Human, Mouse, Rat, Rabbit, Sheep
Host
116

31

3

2
Rabbit
Compatible Secondaries
Clonality
112

40
Polyclonal
Conjugate
72

15

12

9

7

5

3

3

3

3

3

3

2

2

2

2

2

1

1

1

1
This FGF2 antibody is un-conjugated
Application
107

61

51

33

25

25

20

17

16

15

10

9

7

7

3

1

1

1

1

1

1

1

1
Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Cross-Reactivity

Human, Mouse, Rabbit, Rat, Sheep

Predicted Reactivity

Cow,Chicken

Purification

Purified by Protein A.

Immunogen

KLH conjugated synthetic peptide derived from mouse FGF2

Isotype

IgG
anti-Fibroblast Growth Factor 2 (Basic) (FGF2) (AA 143-288) antibody
FGF2 Reactivity: Human WB, IHC, IF Host: Rabbit Polyclonal unconjugated

anti-Fibroblast Growth Factor 2 (Basic) (FGF2) (AA 159-288) antibody
FGF2 Reactivity: Human WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated

anti-Fibroblast Growth Factor 2 (Basic) (FGF2) antibody
FGF2 Reactivity: Human, Mouse, Rat WB, IHC, IF Host: Rabbit Polyclonal unconjugated

anti-Fibroblast Growth Factor 2 (Basic) (FGF2) antibody
KO Validated FGF2 Reactivity: Human WB, IHC, IF Host: Rabbit Monoclonal unconjugated

anti-Fibroblast Growth Factor 2 (Basic) (FGF2) (Middle Region) antibody
FGF2 Reactivity: Human, Mouse, Rat, Rabbit, Dog, Sheep, Cow, Guinea Pig, Zebrafish (Danio rerio), Horse WB, IHC Host: Rabbit Polyclonal unconjugated

anti-Fibroblast Growth Factor 2 (Basic) (FGF2) (AA 26-153) antibody
FGF2 Reactivity: Rabbit WB, IHC, IP, ICC Host: Guinea Pig Polyclonal unconjugated

anti-Fibroblast Growth Factor 2 (Basic) (FGF2) (C-Term) antibody
FGF2 Reactivity: Human, Mouse, Rat WB, ELISA, IHC, ICC, IF Host: Rabbit Polyclonal unconjugated

anti-Fibroblast Growth Factor 2 (Basic) (FGF2) (AA 189-288) antibody
FGF2 Reactivity: Human WB, ELISA, FACS Host: Mouse Monoclonal 1A9B2 unconjugated

anti-Fibroblast Growth Factor 2 (Basic) (FGF2) (AA 143-288) antibody
FGF2 Reactivity: Human WB, ELISA, ICC Host: Mouse Monoclonal 1D6B5 unconjugated

anti-Fibroblast Growth Factor 2 (Basic) (FGF2) (AA 143-288) antibody
FGF2 Reactivity: Human WB, ELISA, IHC Host: Rabbit Polyclonal unconjugated

Application Notes

WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions

For Research Use only
Format

Liquid

Concentration

1 μg/μL

Buffer

0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative

ProClin

Precaution of Use

This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage

4 °C,-20 °C

Storage Comment

Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date

12 months
Zhang, Jiang, Chen, Hu, Yang, Liu et al.: "Silica-coated magnetic nanoparticles labeled endothelial progenitor cells alleviate ischemic myocardial injury and improve long-term cardiac function with magnetic field guidance in rats with ..." in: Journal of cellular physiology, Vol. 234, Issue 10, pp. 18544-18559, (2020) (PubMed).

Liu, Lu, Chen, Zhang, Wang, Li, Zhang: "B-cell leukemia/lymphoma 10 promotes angiogenesis in an experimental corneal neovascularization model." in: Eye (London, England), Vol. 32, Issue 7, pp. 1220-1231, (2019) (PubMed).

Peng, Zhang, Zhang, Zhao, Dong: "Expression of osteoprotegerin and receptor activator for the nuclear factor-κB ligand in XACB/LV-bFGF/MSCs transplantation for repair of rabbit femoral head defect necrosis." in: Journal of cellular biochemistry, (2018) (PubMed).

Eren, Turgut, Akin, Demir: "The Suppression of Wound Healing Response with Sirolimus and Sunitinib Following Experimental Trabeculectomy in a Rabbit Model." in: Current eye research, Vol. 41, Issue 3, pp. 367-76, (2016) (PubMed).

Shkurupy, Arkhipov, Neshchadim, Akhramenko, Troitskii: "In vitro effects of nanosized diamond particles on macrophages." in: Bulletin of experimental biology and medicine, Vol. 158, Issue 4, pp. 500-3, (2015) (PubMed).

He, Qi, Jia, Wang, Wang, Song, Fu, Li, Luo: "Tumor cell-secreted angiogenin induces angiogenic activity of endothelial cells by suppressing miR-542-3p." in: Cancer letters, Vol. 368, Issue 1, pp. 115-25, (2015) (PubMed).

Lee, Lee, Kim, Yang: "Anti-neovascular effect of chondrocyte-derived extracellular matrix on corneal alkaline burns in rabbits." in: Graefe's archive for clinical and experimental ophthalmology, Vol. 252, Issue 6, pp. 951-61, (2014) (PubMed).

Turgut, Eren, Akin, Bilir Can, Demir: "Impact of trastuzumab on wound healing in experimental glaucoma surgery." in: Clinical & experimental ophthalmology, (2014) (PubMed).

Turgut, Eren, Ak?n, Demir, Kobat: "Topical infliximab for the suppression of wound healing following experimental glaucoma filtration surgery." in: Drug design, development and therapy, Vol. 8, pp. 421-9, (2014) (PubMed).

Sun, Pan, Shi, Zhang, Zhang, Ye, Liu, Zhang, Zhong, Yuan: "Structural integrity, immunogenicity and biomechanical evaluation of rabbit decelluarized tracheal matrix." in: Journal of biomedical materials research. Part A, (2014) (PubMed).

Wang, Gao, Xiong, Hu, Liu, He: "VEGF and BFGF Expression and Histological Characteristics of the Bone-Tendon Junction during Acute Injury Healing." in: Journal of sports science & medicine, Vol. 13, Issue 1, pp. 15-21, (2014) (PubMed).

Chen, Wang, Chen, Ma: "Altered TGF-?2 and bFGF expression in scleral desmocytes from an experimentally-induced myopia guinea pig model." in: Graefe's archive for clinical and experimental ophthalmology, Vol. 251, Issue 4, pp. 1133-44, (2013) (PubMed).

Pan, Wang, Xiang, Shao: "Delta-like 1 serves as a new target and contributor to liver fibrosis down-regulated by mesenchymal stem cell transplantation." in: The Journal of biological chemistry, Vol. 286, Issue 14, pp. 12340-8, (2011) (PubMed).

Zhao, Cao, Liu, Xiao, Tang, Wang, Liang: "Effects of recombinant human endostatin on peritoneal angiogenesis in peritoneal dialysis rats." in: Nephrology (Carlton, Vic.), Vol. 16, Issue 6, pp. 599-606, (2011) (PubMed).

Gao, Zhao, Liang, Li, Cao, Liu: "Effect of peritoneal dialysis on expression of vascular endothelial growth factor, basic fibroblast growth factor and endostatin of the peritoneum in peritoneal dialysis patients." in: Nephrology (Carlton, Vic.), Vol. 16, Issue 8, pp. 736-42, (2011) (PubMed).

Liu, Xu, Yang, Chen, Liu, Li, Li: "Analysis of olfactory ensheathing glia transplantation-induced repair of spinal cord injury by electrophysiological, behavioral, and histochemical methods in rats." in: Journal of molecular neuroscience : MN, Vol. 41, Issue 1, pp. 25-9, (2010) (PubMed).
Target

FGF2 (Fibroblast Growth Factor 2 (Basic) (FGF2))

Alternative Name

bFGF (FGF2 Products)

Synonyms

BFGF antibody, FGF-2 antibody, FGFB antibody, HBGF-2 antibody, Fgf-2 antibody, Fgfb antibody, bFGF antibody, fibroblast growth factor 2 antibody, fibroblast growth factor 2 (basic) antibody, FGF2 antibody, Fgf2 antibody, fgf2 antibody

Background

Synonyms: Fgfb, bFGF, Fgf-2, Fibroblast growth factor 2, Basic fibroblast growth factor, Heparin-binding growth factor 2, HBGF-2, Fgf2
Background: Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro (By similarity).

Gene ID

14173

UniProt

P09038

Pathways

RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, C21-Steroid Hormone Metabolic Process, Inositol Metabolic Process, Glycosaminoglycan Metabolic Process, Protein targeting to Nucleus, S100 Proteins