FKBP1A antibody (C-Term)
(2 references)-
- Target See all FKBP1A Antibodies
- FKBP1A (FK506 Binding Protein 1A, 12kDa (FKBP1A))
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Binding Specificity
- AA 55-83, C-Term
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This FKBP1A antibody is un-conjugated
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Application
- Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Predicted Reactivity
- B, Rb
- Purification
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
- Immunogen
- This FKBP1A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 55-83 amino acids from the C-terminal region of human FKBP1A.
- Clone
- RB19307
- Isotype
- Ig Fraction
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anti-FK506 Binding Protein 1A, 12kDa (FKBP1A) (AA 1-108) antibody
FKBP1A Reactivity: Human WB, ELISA Host: Mouse Monoclonal 1E5-A12 unconjugated
anti-FK506 Binding Protein 1A, 12kDa (FKBP1A) (AA 1-108) antibodyFKBP1A Reactivity: Human WB, IHC Host: Rabbit Polyclonal unconjugated
anti-FK506 Binding Protein 1A, 12kDa (FKBP1A) (AA 2-103) antibodyFKBP1A Reactivity: Human WB, IHC, ELISA, IF Host: Rabbit Polyclonal unconjugated
anti-FK506 Binding Protein 1A, 12kDa (FKBP1A) antibodyFKBP1A Reactivity: Human, Mouse, Rat IHC Host: Rabbit Polyclonal unconjugated
anti-FK506 Binding Protein 1A, 12kDa (FKBP1A) (AA 2-108) antibodyFKBP1A Reactivity: Human WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated
anti-FK506 Binding Protein 1A, 12kDa (FKBP1A) (AA 2-108) antibodyFKBP1A Reactivity: Human WB, IHC, IP, ICC Host: Mouse Monoclonal C2 unconjugated
anti-FK506 Binding Protein 1A, 12kDa (FKBP1A) (N-Term) antibodyFKBP1A Reactivity: Human, Mouse, Rat WB, IHC, ELISA Host: Rabbit Polyclonal unconjugated
anti-FK506 Binding Protein 1A, 12kDa (FKBP1A) (AA 43-74) antibodyFKBP1A Reactivity: Human WB, IHC (p) Host: Rabbit Polyclonal RB14521 unconjugated
anti-FK506 Binding Protein 1A, 12kDa (FKBP1A) (AA 43-74) antibodyFKBP1A Reactivity: Human WB, IHC, ELISA Host: Rabbit Polyclonal unconjugated
anti-FK506 Binding Protein 1A, 12kDa (FKBP1A) antibodyFKBP1A Reactivity: Human WB, IHC, FACS Host: Rabbit Polyclonal unconjugated
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- Application Notes
- WB: 1:1000. WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Expiry Date
- 6 months
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: "FK506 binding protein 12 differentially accelerates fibril formation of wild type alpha-synuclein and its clinical mutants A30P or A53T." in: Journal of neurochemistry, Vol. 106, Issue 1, pp. 121-33, (2008) (PubMed).
: "A new pharmacologic action of CCI-779 involves FKBP12-independent inhibition of mTOR kinase activity and profound repression of global protein synthesis." in: Cancer research, Vol. 68, Issue 8, pp. 2934-43, (2008) (PubMed).
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: "FK506 binding protein 12 differentially accelerates fibril formation of wild type alpha-synuclein and its clinical mutants A30P or A53T." in: Journal of neurochemistry, Vol. 106, Issue 1, pp. 121-33, (2008) (PubMed).
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- Target
- FKBP1A (FK506 Binding Protein 1A, 12kDa (FKBP1A))
- Alternative Name
- FKBP1A (FKBP1A Products)
- Synonyms
- 12kDa antibody, FKBP12 antibody, FKBP12-T1 antibody, FKBP12-T2 antibody, Fkbp antibody, Fkbp1 antibody, mFKBP1 antibody, mFKBP12 antibody, FKBP-12 antibody, FKBP-1A antibody, FKBP1 antibody, Rotamase antibody, Fkbp12 antibody, ARABIDOPSIS THALIANA FK506-BINDING PROTEIN 12 antibody, ATFKBP12 antibody, FK506-binding protein 12 antibody, IMMUNOPHILIN antibody, MSJ1.19 antibody, MSJ1_19 antibody, PKC12 antibody, PKCI2 antibody, PPIASE antibody, FKBP1B antibody, Fkbp2 antibody, fj02g10 antibody, zgc:73373 antibody, wu:fj02g10 antibody, FKBP1A antibody, Bmfkbp13 antibody, zgc:103752 antibody, FK506 binding protein 1a antibody, FK506 binding protein 1A antibody, FK506-binding protein antibody, FK506-binding protein 12 antibody, FK506 binding protein 1Aa antibody, FK506 binding protein 1C antibody, FK506-binding protein 59 antibody, FK506 binding protein like antibody, FK506 binding protein 1A L homeolog antibody, FK506 binding protein 1Ab antibody, Fkbp1a antibody, FKBP1A antibody, Fkbp12 antibody, FKBP12 antibody, fkbp1aa antibody, FKBP1C antibody, EHI_180160 antibody, LOC5573443 antibody, Fkbp13 antibody, FKBPL antibody, fkbp1a.L antibody, fkbp1ab antibody
- Background
- FKBP12 is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. The protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin. It interacts with several intracellular signal transduction proteins including type I TGF-beta receptor. It also interacts with multiple intracellular calcium release channels, and coordinates multi-protein complex formation of the tetrameric skeletal muscle ryanodine receptor. In mouse, deletion of this homologous gene causes congenital heart disorder known as noncompaction of left ventricular myocardium.
- Molecular Weight
- 11951
- NCBI Accession
- NP_000792, NP_463460
- UniProt
- P62942
- Pathways
- Negative Regulation of Transporter Activity, Methionine Biosynthetic Process
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