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NLRP1 antibody (AA 1000-1100)

NLRP1 Reactivity: Human WB, IHC, IF Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7268935
  • Target See all NLRP1 Antibodies
    NLRP1 (NLR Family, Pyrin Domain Containing 1 (NLRP1))
    Binding Specificity
    • 15
    • 5
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    AA 1000-1100
    Reactivity
    • 37
    • 18
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 35
    • 2
    • 1
    Rabbit
    Clonality
    • 38
    Polyclonal
    Conjugate
    • 17
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This NLRP1 antibody is un-conjugated
    Application
    • 28
    • 13
    • 13
    • 11
    • 6
    • 6
    • 5
    • 4
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
    Purpose
    NLRP1 Rabbit pAb
    Sequence
    TGEMSNSTSS LKRQRLGSER AASHVAQANL KLLDVSKIFP IAEIAGKSHE ESSPEVVPVE LLCVPSPASQ GDLHTKPLGT DDDFWGPTGP VATEVVDKEK N
    Cross-Reactivity
    Human, Mouse, Rat
    Characteristics
    Polyclonal Antibodies
    Purification
    Affinity purification
    Immunogen
    A synthetic peptide corresponding to a sequence within amino acids 1000-1100 of human NLRP1 (NP_001028225.1).
    Isotype
    IgG
  • Application Notes
    WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    NLRP1 (NLR Family, Pyrin Domain Containing 1 (NLRP1))
    Alternative Name
    NLRP1 (NLRP1 Products)
    Synonyms
    CARD7 antibody, CIDED antibody, CLR17.1 antibody, DEFCAP antibody, DEFCAP-L/S antibody, NAC antibody, NALP1 antibody, PP1044 antibody, SLEV1 antibody, VAMAS1 antibody, NLR family pyrin domain containing 1 antibody, NLRP1 antibody, Nlrp1 antibody
    Background
    This gene encodes a member of the Ced-4 family of apoptosis proteins. Ced-family members contain a caspase recruitment domain (CARD) and are known to be key mediators of programmed cell death. The encoded protein contains a distinct N-terminal pyrin-like motif, which is possibly involved in protein-protein interactions. This protein interacts strongly with caspase 2 and weakly with caspase 9. Overexpression of this gene was demonstrated to induce apoptosis in cells. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene, but the biological validity of some variants has not been determined.,NLRP1,AIADK,CARD7,CIDED,CLR17.1,DEFCAP,DEFCAP-L/S,MSPC,NAC,NALP1,PP1044,SLEV1,VAMAS1,Cell Biology & Developmental Biology,Apoptosis,Caspases,NLRP1
    Molecular Weight
    46kDa/83kDa/154-165kDa
    Gene ID
    22861
    UniProt
    Q9C000
    Pathways
    Positive Regulation of Endopeptidase Activity, Inflammasome
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