SARM1 antibody (AA 340-380)
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- Target See all SARM1 Antibodies
- SARM1 (Sterile alpha and TIR Motif Containing 1 (SARM1))
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Binding Specificity
- AA 340-380
- Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This SARM1 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Cross-Reactivity
- Human, Mouse, Rat
- Purification
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human SARM1
- Isotype
- IgG
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anti-Sterile alpha and TIR Motif Containing 1 (SARM1) (C-Term) antibody
SARM1 Reactivity: Human, Mouse WB, IHC (p), IF, ICC, IHC Host: Rabbit Polyclonal unconjugated
anti-Sterile alpha and TIR Motif Containing 1 (SARM1) antibodySARM1 Reactivity: Human WB, IP Host: Rabbit Polyclonal unconjugated
anti-Sterile alpha and TIR Motif Containing 1 (SARM1) (C-Term) antibodySARM1 Reactivity: Human, Mouse WB, IF, EIA Host: Rabbit Polyclonal unconjugated
anti-Sterile alpha and TIR Motif Containing 1 (SARM1) (AA 93-292) antibodySARM1 Reactivity: Human IP, IHC (p) Host: Mouse Monoclonal Sarmy-1 unconjugated
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- Application Notes
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WB 1:300-5000
IHC-P 1:200-400
IF(IHC-P) 1:50-200 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Storage Comment
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- Expiry Date
- 12 months
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- Target
- SARM1 (Sterile alpha and TIR Motif Containing 1 (SARM1))
- Alternative Name
- SARM1 (SARM1 Products)
- Synonyms
- A830091I15Rik antibody, C78606 antibody, MyD885 antibody, Sarm antibody, MyD88-5 antibody, SAMD2 antibody, SARM antibody, sterile alpha and TIR motif containing 1 antibody, sterile alpha and HEAT/Armadillo motif containing 1 antibody, SARM1 antibody, Sarm1 antibody, sarm1 antibody
- Background
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Synonyms: SARM, SAMD2, MyD88-5, Sterile alpha and TIR motif-containing protein 1, Sterile alpha and Armadillo repeat protein, Sterile alpha motif domain-containing protein 2, SAM domain-containing protein 2, Tir-1 homolog, SARM1, KIAA0524
Background: Negative regulator of MYD88- and TRIF-dependent toll-like receptor signaling pathway which plays a pivotal role in activating axonal degeneration following injury. Promotes Wallerian degeneration an injury-induced axonal death pathway which involves degeneration of an axon distal to the injury site. Can activate neuronal death in response to stress. Regulates dendritic arborization through the MAPK4-JNK pathway. Involved in innate immune response. Inhibits both TICAM1/TRIF- and MYD88-dependent activation of JUN/AP-1, TRIF-dependent activation of NF-kappa-B and IRF3, and the phosphorylation of MAPK14/p38.
- Gene ID
- 23098
- UniProt
- Q6SZW1
- Pathways
- TLR Signaling, Activation of Innate immune Response, Toll-Like Receptors Cascades
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