SMG6 antibody (AA 251-511)
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- Target See all SMG6 Antibodies
- SMG6 (Smg-6 Homolog, Nonsense Mediated mRNA Decay Factor (SMG6))
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Binding Specificity
- AA 251-511
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This SMG6 antibody is un-conjugated
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Application
- ELISA, Immunofluorescence (IF), Immunohistochemistry (IHC)
- Cross-Reactivity
- Human
- Purification
- >95%, Protein G purified
- Immunogen
- Recombinant Human Telomerase-binding protein EST1A protein (251-511AA)
- Isotype
- IgG
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anti-Smg-6 Homolog, Nonsense Mediated mRNA Decay Factor (SMG6) (AA 1160-1419) antibody
SMG6 Reactivity: Human WB Host: Rabbit Polyclonal unconjugated
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- Application Notes
- Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200,
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 - Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Target
- SMG6 (Smg-6 Homolog, Nonsense Mediated mRNA Decay Factor (SMG6))
- Alternative Name
- SMG6 (SMG6 Products)
- Synonyms
- AI317223 antibody, AU041178 antibody, EST1A antibody, C17orf31 antibody, SMG-6 antibody, hSMG5/7a antibody, Smg-6 homolog, nonsense mediated mRNA decay factor (C. elegans) antibody, SMG6, nonsense mediated mRNA decay factor antibody, Smg6 antibody, SMG6 antibody
- Background
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Background: Component of the telomerase ribonucleoprotein (RNP) complex that is essential for the replication of chromosome termini. May have a general role in telomere regulation. Promotes in vitro the ability of TERT to elongate telomeres. Overexpression induces telomere uncapping, chromosomal end-to-end fusions (telomeric DNA persists at the fusion points) and did not perturb TRF2 telomeric localization. Binds to the single-stranded 5\'-(GTGTGG)(4)GTGT-3\' telomeric DNA, but not to a telomerase RNA template component (TER).
Aliases: SMG6 antibody, C17orf31 antibody, EST1A antibody, KIAA0732Telomerase-binding protein EST1A antibody, EC 3.1.-.- antibody, EST1-like protein A antibody, Ever shorter telomeres 1A antibody, Smg-6 homolog antibody, Telomerase subunit EST1A antibody, hSmg5/7a antibody
- UniProt
- Q86US8
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