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RPGRIP1L antibody (N-Term)

RPGRIP1L Reactivity: Human, Mouse, Rat WB, IHC, ICC, IF Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6264825
  • Target See all RPGRIP1L Antibodies
    RPGRIP1L (RPGRIP1-Like (RPGRIP1L))
    Binding Specificity
    • 15
    • 1
    N-Term
    Reactivity
    Human, Mouse, Rat
    Host
    • 17
    • 1
    Rabbit
    Clonality
    • 18
    Polyclonal
    Conjugate
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This RPGRIP1L antibody is un-conjugated
    Application
    • 18
    • 13
    • 13
    • 6
    • 3
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF)
    Specificity
    RPGRIP1L Antibody detects endogenous levels of total RPGRIP1L.
    Predicted Reactivity
    Pig,Bovine,Horse,Sheep,Rabbit,Dog
    Purification
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogen
    A synthesized peptide derived from human RPGRIP1L, corresponding to a region within N-terminal amino acids.
    Isotype
    IgG
  • Application Notes
    WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20 °C. Stable for 12 months from date of receipt.
    Expiry Date
    12 months
  • Target
    RPGRIP1L (RPGRIP1-Like (RPGRIP1L))
    Alternative Name
    RPGRIP1L (RPGRIP1L Products)
    Synonyms
    si:ch1073-301i20.1 antibody, mks5 antibody, cors3 antibody, jbts7 antibody, nphp8 antibody, CORS3 antibody, FTM antibody, JBTS7 antibody, MKS5 antibody, NPHP8 antibody, 1700047E16Rik antibody, 4931437C01 antibody, Ftm antibody, Nphp8 antibody, RGD1311099 antibody, RPGRIP1 like antibody, RPGRIP1-like antibody, Protein fantom antibody, Rpgrip1-like antibody, RPGRIP1L antibody, rpgrip1l antibody, mks-5 antibody, Rpgrip1l antibody
    Background

    Description: Negatively regulates signaling through the G-protein coupled thromboxane A2 receptor (TBXA2R) (PubMed:19464661). May be involved in mechanisms like programmed cell death, craniofacial development, patterning of the limbs, and formation of the left-right axis (By similarity). Involved in the organization of apical junctions, the function is proposed to implicate a NPHP1-4-8 module. Does not seem to be strictly required for ciliogenesis (PubMed:19464661). Involved in establishment of planar cell polarity such as in cochlear sensory epithelium and is proposed to implicate stabilization of disheveled proteins (By similarity). Involved in regulation of proteasomal activity at the primary cilium probably implicating association with PSDM2 (By similarity).

    Gene: RPGRIP1L

    Molecular Weight
    151 kDa
    Gene ID
    23322
    UniProt
    Q68CZ1
    Pathways
    DNA Replication, Regulation of G-Protein Coupled Receptor Protein Signaling, Synthesis of DNA
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