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ATP6V0A2 antibody (N-Term)

ATP6V0A2 Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Saccharomyces cerevisiae, Zebrafish (Danio rerio) WB, IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2775376
  • Target See all ATP6V0A2 Antibodies
    ATP6V0A2 (ATPase, H+ Transporting, Lysosomal V0 Subunit A2 (ATP6V0A2))
    Binding Specificity
    • 4
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivity
    Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Saccharomyces cerevisiae, Zebrafish (Danio rerio)
    Host
    • 11
    • 1
    Rabbit
    Clonality
    • 12
    Polyclonal
    Conjugate
    • 9
    • 1
    • 1
    • 1
    This ATP6V0A2 antibody is un-conjugated
    Application
    • 8
    • 7
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Sequence
    INRADIPLPE GEASPPAPPL KQVLEMQEQL QKLEVELREV TKNKEKLRKN
    Predicted Reactivity
    Cow: 86%, Dog: 93%, Guinea Pig: 83%, Horse: 93%, Human: 100%, Mouse: 100%, Pig: 92%, Rat: 100%, Yeast: 79%, Zebrafish: 77%
    Characteristics
    This is a rabbit polyclonal antibody against ATP6V0A2. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the N terminal region of human ATP6V0A2
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 856 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    ATP6V0A2 (ATPase, H+ Transporting, Lysosomal V0 Subunit A2 (ATP6V0A2))
    Alternative Name
    ATP6V0A2 (ATP6V0A2 Products)
    Synonyms
    A2 antibody, ARCL antibody, ARCL2A antibody, ATP6A2 antibody, ATP6N1D antibody, J6B7 antibody, RTF antibody, STV1 antibody, TJ6 antibody, TJ6M antibody, TJ6S antibody, VPH1 antibody, WSS antibody, 8430408C20Rik antibody, AI385560 antibody, ATP6a2 antibody, AW489264 antibody, Atp6n1d antibody, Atp6n2 antibody, C76904 antibody, ISF antibody, SHIF antibody, Stv1 antibody, TJ6s antibody, Tj6 antibody, V-ATPase 116 kDa antibody, V-ATPase a2 antibody, Cc1-3 antibody, J6b7 antibody, atp6v0a2 antibody, si:ch211-199i18.4 antibody, si:ch211-106a19.2 antibody, ATPase H+ transporting V0 subunit a2 antibody, ATPase, H+ transporting, lysosomal V0 subunit A2 antibody, ATPase, H+ transporting, lysosomal V0 subunit a2a antibody, ATPase, H+ transporting, lysosomal V0 subunit a2b antibody, ATP6V0A2 antibody, Atp6v0a2 antibody, atp6v0a2a antibody, atp6v0a2b antibody
    Background
    The multisubunit vacuolar-type proton pump (H(+)-ATPase or V-ATPase) is essential for acidification of diverse cellular components, including endosomes, lysosomes, clathrin-coated vesicles, secretory vesicles, and chromaffin granules, and it is found at high density in the plasma membrane of certain specialized cells. H(+)-ATPases are comprised of a peripheral V(1) domain and an integral membrane V(0) domain, ATP6V0A2 is a component of the V(0) domain.The multisubunit vacuolar-type proton pump (H(+)-ATPase or V-ATPase) is essential for acidification of diverse cellular components, including endosomes, lysosomes, clathrin-coated vesicles, secretory vesicles, and chromaffin granules, and it is found at high density in the plasma membrane of certain specialized cells. H(+)-ATPases are comprised of a peripheral V(1) domain and an integral membrane V(0) domain, ATP6V0A2 is a component of the V(0) domain (Smith et al., 2003 [PubMed 14580332]).[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
    Alias Symbols: ATP6N1D, ATP6a2, J6B7, Stv1, TJ6, TJ6M, TJ6s, Vph1, a2, A2, RTF, WSS, ARCL, STV1, TJ6S, VPH1, ARCL2A, ATP6A2
    Protein Interaction Partner: UBC, RPL10L, PTRH2, ATP6V1D, RPS15, RPS2, SLC25A3, AKT1, ELAVL1, CYTH2,
    Protein Size: 856
    Molecular Weight
    98 kDa
    Gene ID
    23545
    NCBI Accession
    NM_012463, NP_036595
    UniProt
    Q9Y487
    Pathways
    Transition Metal Ion Homeostasis, Proton Transport
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