Plexin B2 antibody (AA 1080-1200)
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- Target See all Plexin B2 (PLXNB2) Antibodies
- Plexin B2 (PLXNB2)
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Binding Specificity
- AA 1080-1200
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This Plexin B2 antibody is un-conjugated
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Application
- ELISA, Western Blotting (WB), Immunohistochemistry (IHC)
- Cross-Reactivity
- Human, Mouse
- Purification
- Antigen Affinity Purified
- Immunogen
- Recombinant Human Plexin-B2 protein (1080-1200AA)
- Isotype
- IgG
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anti-Plexin B2 (PLXNB2) (AA 1458-1673) antibody
PLXNB2 Reactivity: Human ELISA, WB Host: Rabbit Polyclonal unconjugated
anti-Plexin B2 (PLXNB2) (AA 1506-1611) antibodyPLXNB2 Reactivity: Human ELISA, WB Host: Mouse Polyclonal unconjugated
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- Application Notes
- Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200,
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Target
- Plexin B2 (PLXNB2)
- Alternative Name
- PLXNB2 (PLXNB2 Products)
- Synonyms
- PLXNB2 antibody, MM1 antibody, Nbla00445 antibody, PLEXB2 antibody, dJ402G11.3 antibody, 1110007H23Rik antibody, Debt antibody, mKIAA0315 antibody, plexin B2 antibody, plexin B2 S homeolog antibody, PLXNB2 antibody, plxnb2.S antibody, plxnb2 antibody, Plxnb2 antibody
- Background
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Background: Cell surface receptor for SEMA4C, SEMA4D and SEMA4G that plays an important role in cell-cell signaling. Binding to class 4 semaphorins promotes downstream activation of RHOA and phosphorylation of ERBB2 at \\\'Tyr-1248\\\'. Required for normal differentiation and migration of neuronal cells during brain corticogenesis and for normal embryonic brain development. Regulates the migration of cerebellar granule cells in the developing brain. Plays a role in RHOA activation and subsequent changes of the actin cytoskeleton. Plays a role in axon guidance, invasive growth and cell migration. May modulate the activity of RAC1 and CDC42. Down-regulates macrophage migration in wound-healing assays (in vitro) (By similarity).
Aliases: PLXNB2 antibody, KIAA0315 antibody, Plexin-B2 antibody, MM1 antibody
- UniProt
- O15031
- Pathways
- Tube Formation
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