ARID1B antibody (Internal Region)
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- Target See all ARID1B Antibodies
- ARID1B (AT Rich Interactive Domain 1B (SWI1-Like) (ARID1B))
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Binding Specificity
- Internal Region
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Reactivity
- Human, Rat, Mouse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This ARID1B antibody is un-conjugated
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Application
- Western Blotting (WB), Immunofluorescence (IF), ELISA, Immunocytochemistry (ICC)
- Specificity
- BAF250B Antibody detects endogenous levels of total BAF250B.
- Predicted Reactivity
- Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken
- Purification
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide derived from human BAF250B, corresponding to a region within the internal amino acids.
- Isotype
- IgG
- Top Product
- Discover our top product ARID1B Primary Antibody
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anti-AT Rich Interactive Domain 1B (SWI1-Like) (ARID1B) (AA 1364-1460) antibody
ARID1B Reactivity: Human WB, IF, ELISA, IHC (p) Host: Mouse Monoclonal 2D2 unconjugated
anti-AT Rich Interactive Domain 1B (SWI1-Like) (ARID1B) (AA 400-650) antibodyARID1B Reactivity: Human WB, IF, IHC Host: Rabbit Polyclonal unconjugated
anti-AT Rich Interactive Domain 1B (SWI1-Like) (ARID1B) antibodyARID1B Reactivity: Human ELISA, IHC Host: Rabbit Polyclonal unconjugated
anti-AT Rich Interactive Domain 1B (SWI1-Like) (ARID1B) antibodyARID1B Reactivity: Human, Rat, Mouse IF Host: Rabbit Polyclonal unconjugated
anti-AT Rich Interactive Domain 1B (SWI1-Like) (ARID1B) (Center) antibodyARID1B Reactivity: Human, Rat, Mouse, Pig WB, IF, IHC, IC Host: Rabbit Polyclonal unconjugated
anti-AT Rich Interactive Domain 1B (SWI1-Like) (ARID1B) (AA 1501-1600) antibodyARID1B Reactivity: Mouse WB, ELISA, IHC (p), IF (cc), IF (p), ICC, IHC (fro) Host: Rabbit Polyclonal unconjugated
anti-AT Rich Interactive Domain 1B (SWI1-Like) (ARID1B) (Internal Region) antibodyARID1B Reactivity: Human, Rat WB, IF, ELISA, IHC Host: Rabbit Polyclonal unconjugated
anti-AT Rich Interactive Domain 1B (SWI1-Like) (ARID1B) (AA 1364-1461) antibodyARID1B Reactivity: Human WB, IF, ELISA, IHC, IHC (p) Host: Mouse Monoclonal 2D2 unconjugated
anti-AT Rich Interactive Domain 1B (SWI1-Like) (ARID1B) (AA 1371-1420) antibodyARID1B Reactivity: Human, Rat WB, IF, ELISA Host: Rabbit Polyclonal unconjugated
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- Application Notes
- WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20 °C. Stable for 12 months from date of receipt.
- Expiry Date
- 12 months
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- Target
- ARID1B (AT Rich Interactive Domain 1B (SWI1-Like) (ARID1B))
- Alternative Name
- ARID1B (ARID1B Products)
- Synonyms
- fd07d11 antibody, si:dkey-60a16.3 antibody, wu:fd07d11 antibody, 8030481M12 antibody, 9330189K18Rik antibody, AI836955 antibody, Ardi1b antibody, B230217J03Rik antibody, mKIAA1235 antibody, 6A3-5 antibody, Smcf1 antibody, smcf-1 antibody, BAF250B antibody, BRIGHT antibody, DAN15 antibody, ELD/OSA1 antibody, MRD12 antibody, OSA2 antibody, P250R antibody, AT rich interactive domain 1B (SWI1-like) antibody, AT rich interactive domain 1B (SWI-like) antibody, AT-rich interaction domain 1B antibody, arid1b antibody, Arid1b antibody, ARID1B antibody
- Background
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Description: Involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology). Component of SWI/SNF chromatin remodeling complexes that carry out key enzymatic activities, changing chromatin structure by altering DNA-histone contacts within a nucleosome in an ATP-dependent manner. Belongs to the neural progenitors-specific chromatin remodeling complex (npBAF complex) and the neuron-specific chromatin remodeling complex (nBAF complex). During neural development a switch from a stem/progenitor to a postmitotic chromatin remodeling mechanism occurs as neurons exit the cell cycle and become committed to their adult state. The transition from proliferating neural stem/progenitor cells to postmitotic neurons requires a switch in subunit composition of the npBAF and nBAF complexes. As neural progenitors exit mitosis and differentiate into neurons, npBAF complexes which contain ACTL6A/BAF53A and PHF10/BAF45A, are exchanged for homologous alternative ACTL6B/BAF53B and DPF1/BAF45B or DPF3/BAF45C subunits in neuron-specific complexes (nBAF). The npBAF complex is essential for the self-renewal/proliferative capacity of the multipotent neural stem cells. The nBAF complex along with CREST plays a role regulating the activity of genes essential for dendrite growth (By similarity). Binds DNA non-specifically (PubMed:14982958, PubMed:15170388).
Gene: ARID1B
- Molecular Weight
- 170 kDa
- Gene ID
- 57492
- UniProt
- Q8NFD5
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