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c-MYC antibody (AA 360-440)

Name: c-MYC antibody (AA 360-440)
Brand: antibodies-online
SKU: ABIN7214262
Price: 315.92 USD
Availability: InStock

MYC Reactivity: Human, Mouse, Rat WB, ELISA, IF, IHC (p) Host: Rabbit Polyclonal unconjugated

Western Blot analysis of various cells using c-Myc Polyclonal Antibody diluted at 1:1000.

Immunohistochemical analysis of paraffin-embedded rat testis tissue.

IHC

Immunofluorescence analysis of human lung tissue.

Immunofluorescence analysis of rat lung tissue.

Immunohistochemical analysis of paraffin-embedded human uterus tissue.

IHC

Immunohistochemical analysis of paraffin-embedded mouse testis tissue.

IHC

6 images

Catalog No. ABIN7214262

Datasheet as PDF

Target See all c-MYC (MYC) Antibodies

c-MYC (MYC) (Myc Proto-Oncogene protein (MYC))
Binding Specificity
55

44

43

40

24

21

19

16

15

11

11

11

10

7

7

6

6

4

3

3

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 360-440
Reactivity
372

169

122

15

14

13

13

13

9

9

8

6

6

6

5

4

3

3

2

2

2

1

1

1

1

1
Human, Mouse, Rat
Host
294

97

7

3

2

1
Rabbit
Compatible Secondaries
Clonality
287

116
Polyclonal
Conjugate
193

32

27

26

10

9

9

9

9

9

9

7

5

5

5

5

5

3

2

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1
This c-MYC antibody is un-conjugated
Application
303

141

96

83

79

63

58

28

26

17

14

13

12

11

7

4

2

1

1

1
Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purpose

c-Myc Polyclonal Antibody

Specificity

C-Myc Polyclonal Antibody detects endogenous levels of c-Myc protein.

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen

Synthesized peptide derived from the C-terminal region of human c-Myc at AA range: 360-440

Isotype

IgG

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MYC Reactivity: Human WB, IHC, ELISA, IF Host: Rabbit Polyclonal unconjugated

Application Notes

Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), IF (1:200-1:1000), ELISA (1:40000). Not yet tested in other applications.

Comment

Primary Antibody

Restrictions

For Research Use only
Format

Liquid

Concentration

1 mg/mL

Buffer

PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Preservative

Sodium azide

Precaution of Use

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage

-20 °C

Storage Comment

Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Target

c-MYC (MYC) (Myc Proto-Oncogene protein (MYC))

Alternative Name

c-Myc (MYC Products)

Synonyms

MRTL antibody, MYCC antibody, bHLHe39 antibody, c-Myc antibody, CMYC antibody, c-myc antibody, C-MYC antibody, LOC100136746 antibody, ARC antibody, B430311C09Rik antibody, MYC antibody, NOP antibody, Nop30 antibody, RNCMYC antibody, mMyc antibody, AU016757 antibody, Myc2 antibody, Niard antibody, Nird antibody, cmyc antibody, zc-myc antibody, c-myc II antibody, myc-B antibody, myc2 antibody, myc1 antibody, CMyc antibody, zgc:55680 antibody, CG10798 antibody, D-Myc antibody, DM antibody, DMYc antibody, Dm antibody, Dmel\CG10798 antibody, Dmyc antibody, EG:BACN5I9.1 antibody, anon-WO03040301.171 antibody, bHLHe57 antibody, c-MYC antibody, d-myc antibody, dMYC antibody, dMyc antibody, dMyc1 antibody, da antibody, dm antibody, dm/dMyc antibody, dm/myc antibody, dmyc antibody, dmyc1 antibody, l(1)G0139 antibody, l(1)G0354 antibody, l(1)G0359 antibody, myc antibody, MYC proto-oncogene, bHLH transcription factor antibody, v-myc myelocytomatosis viral oncogene homolog antibody, nucleolar protein 3 (apoptosis repressor with CARD domain) antibody, myelocytomatosis oncogene antibody, MYC proto-oncogene, bHLH transcription factor a antibody, MYC proto-oncogene, bHLH transcription factor L homeolog antibody, MYC proto-oncogene, bHLH transcription factor S homeolog antibody, v-myc myelocytomatosis viral oncogene homolog (avian) antibody, MYC proto-oncogene, bHLH transcription factor b antibody, CG10798 gene product from transcript CG10798-RB antibody, MYC antibody, LOC100136746 antibody, Nol3 antibody, Myc antibody, myca antibody, myc.L antibody, myc.S antibody, mycb antibody

Background

Rabbit Anti-c-Myc Polyclonal Antibody,MYC, BHLHE39, Myc proto-oncogene protein, Class E basic helix-loop-helix protein 39, bHLHe39, Proto-oncogene c-Myc, Transcription factor p64,V-myc avian myelocytomatosis viral oncogene homolog encoded by MYC is a multifunctional, nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. It functions as a transcription factor that regulates transcription of specific target genes. Mutations, overexpression, rearrangement and translocation of this gene have been associated with a variety of hematopoietic tumors, leukemias and lymphomas, including Burkitt lymphoma. There is evidence to show that alternative translation initiations from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site result in the production of two isoforms with distinct N-termini. The synthesis of non-AUG initiated protein is suppressed in Burkitt's lymphomas, suggesting its importance in the normal function of MYC.,Myc proto-oncogene protein

Molecular Weight

observerd band 50,(also ~60kDa in some samples)kDa

Gene ID

4609

UniProt

P01106

Pathways

p53 Signaling, Cell Division Cycle, Sensory Perception of Sound, Transition Metal Ion Homeostasis, Mitotic G1-G1/S Phases, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process, Positive Regulation of Response to DNA Damage Stimulus, Warburg Effect