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PDGF-BB Homodimer (AA 151-241) antibody

Reactivity: Human, Mouse, Rat, Chicken WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN674874
  • Target
    PDGF-BB Homodimer
    Binding Specificity
    • 14
    • 8
    • 6
    • 3
    • 2
    • 1
    • 1
    • 1
    AA 151-241
    Reactivity
    • 38
    • 24
    • 20
    • 14
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Mouse, Rat, Chicken
    Host
    • 41
    • 4
    • 1
    Rabbit
    Clonality
    • 42
    • 4
    Polyclonal
    Conjugate
    • 19
    • 7
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Un-conjugated
    Application
    • 46
    • 16
    • 12
    • 12
    • 11
    • 6
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Cross-Reactivity
    Chicken, Human, Mouse, Rat
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human PDGF-B
    Isotype
    IgG
  • Application Notes
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Expiry Date
    12 months
  • Cipriani, Di Benedetto, Dietrich, Ruscitti, Liakouli, Carubbi, Pantano, Berardicurti, Sgonc, Giacomelli: "Searching for a good model for systemic sclerosis: the molecular profile and vascular changes occurring in UCD-200 chickens strongly resemble the early phase of human systemic sclerosis." in: Archives of medical science : AMS, Vol. 12, Issue 4, pp. 828-43, (2016) (PubMed).

  • Target
    PDGF-BB Homodimer
    Alternative Name
    PDGFBB
    Synonyms
    PDGF-2 antibody, PDGF2 antibody, SIS antibody, SSV antibody, c-sis antibody, PDGF-B antibody, Sis antibody, platelet derived growth factor subunit B antibody, platelet derived growth factor, B polypeptide antibody, PDGFB antibody, Pdgfb antibody
    Background

    Synonyms: PDGF BB, PDGF-BB, platelet derived growth factor-BB, Becaplermin, C sis, FLJ12858, Oncogene SIS, PDG B chain, PDGB, PDGF 2, PDGF B, PDGF B chain, PDGF2, PDGFB, PDGFB/COL1A1 fusion gene, Platelet derived growth factor 2, Platelet derived growth factor B chain, Platelet derived growth factor beta, Platelet derived growth factor beta polypeptide, Simian sarcoma viral v sis oncogene homolog, SIS, SSV, V sis platelet derived growth factor beta polypeptide.

    Background: Platelet Derived Growth Factor (PDGF) is the major serum mitogen for cells of mesenchymal origin in humans. The biologically active protein is a dimer composed of two related polypeptides designated A and B, the dimers being connected by disulfide bonds. The PDGF protein has been implicated both directly as well as indirectly in several pathological states including neoplasia, arthritis, arteriosclerosis and bone marrow sclerosis.

    Gene ID
    5155
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