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Vitamin D Receptor antibody (AA 65-180)

Name: Vitamin D Receptor antibody (AA 65-180)
SKU: ABIN682513
Price: 384.62 USD
Availability: InStock

VDR Reactivity: Human, Mouse, Rat WB, IF (cc), IF (p), IHC (p), IHC (fro) Host: Rabbit Polyclonal unconjugated

Formalin-fixed and paraffin embedded rat liver labeled with Anti-Vitamin D Receptor/VDR Polyclonal Antibody, Unconjugated (ABIN682513) at 1:200 followed by conjugation to the secondary antibody and DAB staining.

IHC

Formalin-fixed and paraffin-embedded rat lung labeled with Anti-Vitamin D Receptor/VDR Polyclonal Antibody, Unconjugated (ABIN682513) 1:200, overnight at 4°C, The secondary antibody was Goat Anti-Rabbit IgG, Cy3 conjugated used at 1:200 dilution for 40 minutes at 37°C.

L1 rat brain lysates L2 rat kidney lysates probed with Anti Vitamin D Receptor/VDR Polyclonal Antibody, Unconjugated (ABIN682513) at 1:200 overnight at 4 °C.

SDS

Formalin-fixed and paraffin embedded human brain glioblastoma labeled with Anti-Vitamin D Receptor/VDR Polyclonal Antibody, Unconjugated (ABIN682513) at 1:200 followed by conjugation to the secondary antibody and DAB staining

IHC

4 images

(5 references)

Catalog No. ABIN682513

Datasheet as PDF

Target See all Vitamin D Receptor (VDR) Antibodies

Vitamin D Receptor (VDR)
Binding Specificity
15

14

13

10

7

4

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 65-180
Reactivity
90

52

36

2

1

1

1

1

1
Human, Mouse, Rat
Host
97

11

1

1
Rabbit
Compatible Secondaries
Clonality
91

19
Polyclonal
Conjugate
55

6

5

5

5

5

5

5

3

3

2

2

2

2

2

2

1
This Vitamin D Receptor antibody is un-conjugated
Application
84

32

25

25

15

14

13

10

5

5

4

2

2

1

1
Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Cross-Reactivity

Human, Mouse, Rat

Predicted Reactivity

Cow,Pig,Horse,Chicken,Rabbit

Purification

Purified by Protein A.

Immunogen

KLH conjugated synthetic peptide derived from human Vitamin D Receptor

Isotype

IgG
anti-Vitamin D Receptor (VDR) (AA 1-427) antibody
VDR Reactivity: Human WB, IF Host: Mouse Polyclonal unconjugated

anti-Vitamin D Receptor (VDR) (AA 1-300) antibody
VDR Reactivity: Human WB, IHC, IF Host: Rabbit Polyclonal unconjugated

anti-Vitamin D Receptor (VDR) (AA 377-402), (C-Term) antibody
VDR Reactivity: Human WB, IHC (p) Host: Rabbit Polyclonal unconjugated

anti-Vitamin D Receptor (VDR) (N-Term) antibody
VDR Reactivity: Human WB Host: Rabbit Polyclonal unconjugated

anti-Vitamin D Receptor (VDR) (pSer208) antibody
VDR Reactivity: Human WB, ELISA, IF, ICC Host: Rabbit Polyclonal unconjugated

anti-Vitamin D Receptor (VDR) (Ser208) antibody
VDR Reactivity: Human WB, ELISA, IF, IHC (p) Host: Rabbit Polyclonal unconjugated

anti-Vitamin D Receptor (VDR) (AA 266-422) antibody
VDR Reactivity: Mouse WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated

anti-Vitamin D Receptor (VDR) antibody
VDR Reactivity: Human WB, ELISA, IHC Host: Rabbit Monoclonal 3C7 unconjugated Recombinant Antibody

anti-Vitamin D Receptor (VDR) (AA 1-427) antibody
VDR Reactivity: Human ELISA, IHC (p) Host: Mouse Monoclonal 2F4 unconjugated

anti-Vitamin D Receptor (VDR) (AA 1-428) antibody
VDR Reactivity: Human ELISA, IHC, IHC (p) Host: Mouse Monoclonal 2F4 unconjugated

Application Notes

WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions

For Research Use only
Format

Liquid

Concentration

1 μg/μL

Buffer

0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative

ProClin

Precaution of Use

This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage

4 °C,-20 °C

Storage Comment

Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date

12 months
Wu, Chen, Tian, Zhang, Bian, Cheng: "Serum 25-hydroxyvitamin D inversely associated with blood eosinophils in patients with persistent allergic rhinitis." in: Asia Pacific allergy, Vol. 7, Issue 4, pp. 213-220, (2017) (PubMed).

Zhang, Zhou, Guo, Song, Liu: "1,25-Dihydroxyvitamin D₃ Promotes High Glucose-Induced M1 Macrophage Switching to M2 via the VDR-PPARγ Signaling Pathway." in: BioMed research international, Vol. 2015, pp. 157834, (2016) (PubMed).

Tian, Lv, Yang, Zhang, Yu, Zhu, Xiao, Zhu: "Effects of vitamin D on renal fibrosis in diabetic nephropathy model rats." in: International journal of clinical and experimental pathology, Vol. 7, Issue 6, pp. 3028-37, (2014) (PubMed).

Song, Guo, Zhou, Zhang: "The PI3K/p-Akt signaling pathway participates in calcitriol ameliorating podocyte injury in DN rats." in: Metabolism: clinical and experimental, Vol. 63, Issue 10, pp. 1324-33, (2014) (PubMed).

Zhang, Song, Guo, Zhou: "The novel role of TRPC6 in vitamin D ameliorating podocyte injury in STZ-induced diabetic rats." in: Molecular and cellular biochemistry, (2014) (PubMed).
Target

Vitamin D Receptor (VDR)

Alternative Name

Vitamin D Receptor/VDR (VDR Products)

Synonyms

vdrbeta antibody, vdr0 antibody, LOC100136219 antibody, NR1I1-B antibody, gb:dq017633 antibody, vdr-b antibody, Ci-VDR-b antibody, VDR antibody, LOC100221284 antibody, vdr-A antibody, xVDR antibody, Nr1i1 antibody, vdr antibody, NR1I1 antibody, PPP1R163 antibody, vitamin D (1,25- dihydroxyvitamin D3) receptor antibody, vitamin D receptor antibody, vitamin D3 receptor A antibody, vitamin D receptor b antibody, nuclear receptor VDR-b antibody, vitamin D (1,25- dihydroxyvitamin D3) receptor L homeolog antibody, vitamin D (1,25-dihydroxyvitamin D3) receptor antibody, vitamin D receptor a antibody, vdr antibody, vdr0 antibody, VDR antibody, LOC100136219 antibody, vdrb antibody, vdr-b antibody, vdr.L antibody, Vdr antibody, vdra antibody

Target Type

Chemical

Background

Synonyms: NR1I1, PPP1R163, Vitamin D3 receptor, VDR, 1,25-dihydroxyvitamin D3 receptor, Nuclear receptor subfamily 1 group I member 1
Background: Nuclear hormone receptor. Transcription factor that mediates the action of vitamin D3 by controlling the expression of hormone sensitive genes. Regulates transcription of hormone sensitive genes via its association with the WINAC complex, a chromatin-remodeling complex. Recruited to promoters via its interaction with the WINAC complex subunit BAZ1B/WSTF, which mediates the interaction with acetylated histones, an essential step for VDR-promoter association. Plays a central role in calcium homeostasis.

Gene ID

7421

UniProt

P11473

Pathways

Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway