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CTSC antibody (AA 365-463)

CTSC Reactivity: Rat WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) Host: Rabbit Polyclonal unconjugated

Catalog No. ABIN748898

Datasheet as PDF

Target See all CTSC Antibodies

CTSC (Cathepsin C (CTSC))
Binding Specificity
14

6

4

2

2

1

1

1

1

1

1

1

1

1

1

1

1
AA 365-463
Reactivity
32

18

11

6

3

2

2

2

1

1
Rat
Host
49

5

1
Rabbit
Compatible Secondaries
Clonality
52

2
Polyclonal
Conjugate
28

5

3

2

2

2

2

2

2

2

1

1

1

1

1
This CTSC antibody is un-conjugated
Application
44

20

12

12

9

7

3

2

2

2

2

2

2

2

1
Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Cross-Reactivity

Rat

Predicted Reactivity

Human,Mouse,Dog,Cow,Pig,Horse,Chicken,Rabbit

Purification

Purified by Protein A.

Immunogen

KLH conjugated synthetic peptide derived from human DPP-I

Isotype

IgG

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CTSC Reactivity: Human ELISA, IHC Host: Rabbit Polyclonal unconjugated

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CTSC Reactivity: Human WB, ELISA Host: Rabbit Polyclonal unconjugated

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Verified CTSC Reactivity: Human WB, ELISA, IHC Host: Goat Polyclonal unconjugated

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CTSC Reactivity: Human WB Host: Rabbit Polyclonal unconjugated

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CTSC Reactivity: Human, Mouse, Cow, Monkey WB Host: Rabbit Polyclonal unconjugated

anti-Cathepsin C (CTSC) antibody
CTSC Reactivity: Human WB, ELISA Host: Mouse Monoclonal 14 unconjugated

Application Notes

WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions

For Research Use only
Format

Liquid

Concentration

1 μg/μL

Buffer

0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative

ProClin

Precaution of Use

This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage

4 °C,-20 °C

Storage Comment

Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date

12 months
Target

CTSC (Cathepsin C (CTSC))

Alternative Name

Cathepsin C/DPP1 (CTSC Products)

Synonyms

CPPI antibody, DPP-I antibody, DPP1 antibody, DPPI antibody, HMS antibody, JP antibody, JPD antibody, PALS antibody, PDON1 antibody, PLS antibody, MGC69126 antibody, MGC107782 antibody, AI047818 antibody, CATC antibody, cb912 antibody, ik:tdsubc_1h2 antibody, sb:cb146 antibody, wu:fb34g12 antibody, wu:fj58d01 antibody, cathepsin C antibody, cathepsin C L homeolog antibody, cathepsin CPC1 antibody, CTSC antibody, ctsc.L antibody, ctsc antibody, TP03_0357 antibody, CMU_003360 antibody, CPC1 antibody, NAEGRDRAFT_80477 antibody, NAEGRDRAFT_37577 antibody, Ctsc antibody, Smp_183330 antibody

Background

Synonyms: Dipeptidyl peptidase I, AI047818, CATC, Cathepsin C, Cathepsin J, CPPI, CTSC, Dipeptidyl peptidase 1, Dipeptidyl transferase, DPP I, DPPI, EC 3.4.14.1, HMS, JP, JPD, MGC126959, PALS, PLS.
Background: The protein encoded by this gene, a member of the peptidase C1 family, is a lysosomal cysteine proteinase that appears to be a central coordinator for activation of many serine proteinases in immune/inflammatory cells. It is composed of a dimer of disulfide-linked heavy and light chains, both produced from a single protein precursor, and a residual portion of the propeptide acts as an intramolecular chaperone for the folding and stabilization of the mature enzyme. This enzyme requires chloride ions for activity and can degrade glucagon. Defects in the encoded protein have been shown to be a cause of Papillon-Lefevre syndrome, an autosomal recessive disorder characterized by palmoplantar keratosis and periodontitis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq].

Gene ID

1075