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GABBR1 antibody (AA 52-151)

Name: GABBR1 antibody (AA 52-151)
SKU: ABIN560976
Price: 534.67 USD
Availability: InStock

GABBR1 Reactivity: Human WB, ELISA, IF, RNAi Host: Mouse Monoclonal 2D7 unconjugated

Western Blot detection against Immunogen (36.

Detection limit for recombinant GST tagged GABBR1 is approximately 0.

ELISA

Immunofluorescence of monoclonal antibody to GABBR1 on HeLa cell.

GABBR1 monoclonal antibody (M01), clone 2D7 Western Blot analysis of GABBR1 expression in IMR-32 .

Western Blot analysis of GABBR1 expression in transfected 293T cell line by GABBR1 monoclonal antibody (M01), clone 2D7.

Western blot analysis of GABBR1 over-expressed 293 cell line, cotransfected with GABBR1 Validated Chimera RNAi (Lane 2) or non-transfected control (Lane 1).

6 images

(4 references)

Catalog No. ABIN560976

Datasheet as PDF

Target See all GABBR1 Antibodies

GABBR1 (gamma-aminobutyric Acid (GABA) B Receptor, 1 (GABBR1))
Binding Specificity
17

14

12

8

4

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 52-151
Reactivity
57

52

42

9

7

5

4

3

3

2

2

2

2

1

1
Human
Host
48

19

3

2
Mouse
Compatible Secondaries
Clonality
53

19
Monoclonal
Conjugate
47

3

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
This GABBR1 antibody is un-conjugated
Application
61

20

19

17

15

14

14

12

4

2

2

1

1

1
Western Blotting (WB), ELISA, Immunofluorescence (IF), RNA Interference (RNAi)

Purpose

Mouse monoclonal antibody raised against a partial recombinant GABBR1.

Sequence

AVYIGALFPM SGGWPGGQAC QPAVEMALED VNSRRDILPD YELKLIHHDS KCDPGQATKY LYELLYNDPI KIILMPGCSS VSTLVAEAAR MWNLIVLSYG

Cross-Reactivity

Human

Characteristics

Antibody Reactive Against Recombinant Protein.

Immunogen

GABBR1 (AAH50532, 52 a.a. ~ 151 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Clone

2D7

Isotype

IgG2a
anti-gamma-aminobutyric Acid (GABA) B Receptor, 1 (GABBR1) (C-Term) antibody
GABBR1 Reactivity: Human, Rat, Mouse WB, ELISA, IF, IHC, ICC Host: Rabbit Polyclonal unconjugated

anti-gamma-aminobutyric Acid (GABA) B Receptor, 1 (GABBR1) antibody
GABBR1 Reactivity: Human WB, IF, ICC, IHC (p) Host: Rabbit Polyclonal unconjugated

anti-gamma-aminobutyric Acid (GABA) B Receptor, 1 (GABBR1) (AA 873-977) antibody
GABBR1 Reactivity: Rat WB, IF, ICC Host: Mouse Monoclonal S93A-49 unconjugated

anti-gamma-aminobutyric Acid (GABA) B Receptor, 1 (GABBR1) (AA 873-977) antibody (HRP)
GABBR1 Reactivity: Rat WB, IF, ICC Host: Mouse Monoclonal S93A-49 HRP

anti-gamma-aminobutyric Acid (GABA) B Receptor, 1 (GABBR1) (AA 873-977) antibody (FITC)
GABBR1 Reactivity: Rat WB, IF, ICC Host: Mouse Monoclonal S93A-49 FITC

anti-gamma-aminobutyric Acid (GABA) B Receptor, 1 (GABBR1) (AA 873-977) antibody (Alkaline Phosphatase (AP))
GABBR1 Reactivity: Rat WB, IF, ICC Host: Mouse Monoclonal S93A-49 Alkaline Phosphatase (AP)

anti-gamma-aminobutyric Acid (GABA) B Receptor, 1 (GABBR1) (AA 873-977) antibody (Biotin)
GABBR1 Reactivity: Rat WB, IF, ICC Host: Mouse Monoclonal S93A-49 Biotin

anti-gamma-aminobutyric Acid (GABA) B Receptor, 1 (GABBR1) (AA 873-977) antibody (PE)
GABBR1 Reactivity: Rat WB, IF, ICC Host: Mouse Monoclonal S93A-49 PE

anti-gamma-aminobutyric Acid (GABA) B Receptor, 1 (GABBR1) (AA 873-977) antibody (APC)
GABBR1 Reactivity: Rat WB, IF, ICC Host: Mouse Monoclonal S93A-49 APC

anti-gamma-aminobutyric Acid (GABA) B Receptor, 1 (GABBR1) (AA 873-977) antibody (PerCP)
GABBR1 Reactivity: Rat WB, IF, ICC Host: Mouse Monoclonal S93A-49 PerCP

Application Notes

Optimal working dilution should be determined by the investigator.

Restrictions

For Research Use only
Buffer

In 1x PBS, pH 7.4

Handling Advice

Aliquot to avoid repeated freezing and thawing.

Storage

-20 °C

Storage Comment

Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Dogan Onugoren, Deuretzbacher, Haensch, Hagedorn, Halve, Isenmann, Kramme, Lohner, Melzer, Monotti, Presslauer, Schäbitz, Steffanoni, Stoeck, Strittmatter, Stögbauer, Trinka, von Oertzen, Wiendl et al.: "Limbic encephalitis due to GABAB and AMPA receptor antibodies: a case series. ..." in: Journal of neurology, neurosurgery, and psychiatry, (2014) (PubMed).

Dogan Onugoren, Rauschka, Bien: "Conjoint occurrence of GABAB receptor antibodies in Lambert-Eaton myasthenic syndrome with antibodies to the voltage gated calcium channel." in: Journal of neuroimmunology, Vol. 273, Issue 1-2, pp. 115-6, (2014) (PubMed).

Wang, Chen, Chen, Wolpaw, Chen: "Cortical stimulation causes long-term changes in H-reflexes and spinal motoneuron GABA receptors." in: Journal of neurophysiology, Vol. 108, Issue 10, pp. 2668-78, (2012) (PubMed).

Tse, Su, Chang, Tsang, Yu, Tang, See, Hsueh, Yang, Hao, Li, Wang, Liao, Chen, Lin, Jorgensen, Chang, Shugart: "Genome-wide association study reveals multiple nasopharyngeal carcinoma-associated loci within the HLA region at chromosome 6p21.3." in: American journal of human genetics, Vol. 85, Issue 2, pp. 194-203, (2009) (PubMed).
Target

GABBR1 (gamma-aminobutyric Acid (GABA) B Receptor, 1 (GABBR1))

Alternative Name

GABBR1 (GABBR1 Products)

Synonyms

GABABR1 antibody, GABBR1-3 antibody, GB1 antibody, GPRC3A antibody, dJ271M21.1.1 antibody, dJ271M21.1.2 antibody, gabbr1 antibody, GABBR1 antibody, GABA(B)R1 antibody, GABAB1 antibody, GABAbR1 antibody, bM573K1.1 antibody, gamma-aminobutyric acid type B receptor subunit 1 antibody, gamma-aminobutyric acid (GABA) B receptor, 1a antibody, gamma-aminobutyric acid (GABA) B receptor, 1 antibody, GABBR1 antibody, gabbr1a antibody, gabbr1 antibody, Gabbr1 antibody

Background

Full Gene Name: gamma-aminobutyric acid (GABA) B receptor, 1
Synonyms: FLJ92613,GABAB(1e),GABABR1,GABBR1-3,GPRC3A,dJ271M21.1.1,dJ271M21.1.2,hGB1a

Gene ID

2550

Pathways

Positive Regulation of Peptide Hormone Secretion, cAMP Metabolic Process