OAZ1 antibody
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- Target See all OAZ1 Antibodies
- OAZ1 (Ornithine Decarboxylase Antizyme 1 (OAZ1))
- Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This OAZ1 antibody is un-conjugated
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Application
- Immunohistochemistry (IHC)
- Characteristics
- Polyclonal Antibody
- Purification
- Affinity purification
- Immunogen
- Recombinant fusion protein of human OAZ1 (NP_004143.1).
- Isotype
- IgG
- Top Product
- Discover our top product OAZ1 Primary Antibody
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anti-Ornithine Decarboxylase Antizyme 1 (OAZ1) (AA 1-68) antibody
OAZ1 Reactivity: Human IHC, ELISA Host: Rabbit Polyclonal unconjugated
anti-Ornithine Decarboxylase Antizyme 1 (OAZ1) (AA 2-31), (N-Term) antibodyOAZ1 Reactivity: Human, Mouse, Rat WB Host: Rabbit Polyclonal RB18521 unconjugated
anti-Ornithine Decarboxylase Antizyme 1 (OAZ1) (N-Term) antibodyOAZ1 Reactivity: Human IHC, ELISA Host: Rabbit Polyclonal unconjugated
anti-Ornithine Decarboxylase Antizyme 1 (OAZ1) (AA 120-132) antibodyVerified OAZ1 Reactivity: Human ELISA, WB Host: Goat Polyclonal unconjugated
anti-Ornithine Decarboxylase Antizyme 1 (OAZ1) (AA 1-68) antibodyOAZ1 Reactivity: Human WB Host: Rabbit Polyclonal unconjugated
anti-Ornithine Decarboxylase Antizyme 1 (OAZ1) (N-Term) antibodyOAZ1 Reactivity: Human, Mouse, Rat IHC, WB Host: Rabbit Polyclonal unconjugated
anti-Ornithine Decarboxylase Antizyme 1 (OAZ1) (AA 14-63) antibodyOAZ1 Reactivity: Human, Mouse, Rat IHC, ELISA Host: Rabbit Polyclonal unconjugated
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- Application Notes
- IHC 1:50-1:200
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- OAZ1 (Ornithine Decarboxylase Antizyme 1 (OAZ1))
- Alternative Name
- OAZ1 (OAZ1 Products)
- Background
- The protein encoded by this gene belongs to the ornithine decarboxylase antizyme family, which plays a role in cell growth and proliferation by regulating intracellular polyamine levels. Expression of antizymes requires +1 ribosomal frameshifting, which is enhanced by high levels of polyamines. Antizymes in turn bind to and inhibit ornithine decarboxylase (ODC), the key enzyme in polyamine biosynthesis, thus, completing the auto-regulatory circuit. This gene encodes antizyme 1, the first member of the antizyme family, that has broad tissue distribution, and negatively regulates intracellular polyamine levels by binding to and targeting ODC for degradation, as well as inhibiting polyamine uptake. Antizyme 1 mRNA contains two potential in-frame AUGs, and studies in rat suggest that alternative use of the two translation initiation sites results in N-terminally distinct protein isoforms with different subcellular localization. Alternatively spliced transcript variants have also been noted for this gene.
- Gene ID
- 4946
- UniProt
- P54368
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