CALHM1 antibody (N-Term)
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- Target See all CALHM1 Antibodies
- CALHM1 (Calcium Homeostasis Modulator 1 (CALHM1))
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Binding Specificity
- N-Term
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Reactivity
- Human, Rat, Mouse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This CALHM1 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF), Enzyme Immunoassay (EIA)
- Cross-Reactivity (Details)
- Species reactivity (tested):Human, Mouse, Rat.
- Purification
- Affinity chromatography purified via peptide column
- Immunogen
- 17 amino acid peptide near the amino terminus of Human CALHM1
- Isotype
- IgG
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anti-Calcium Homeostasis Modulator 1 (CALHM1) (AA 202-346) antibody
CALHM1 Reactivity: Human WB, ELISA Host: Rabbit Polyclonal unconjugated
anti-Calcium Homeostasis Modulator 1 (CALHM1) (AA 202-346) antibodyCALHM1 Reactivity: Human IHC, ELISA Host: Rabbit Polyclonal unconjugated
anti-Calcium Homeostasis Modulator 1 (CALHM1) (AA 295-344) antibodyCALHM1 Reactivity: Human, Rat, Mouse, Hamster WB Host: Rabbit Polyclonal unconjugated
anti-Calcium Homeostasis Modulator 1 (CALHM1) (AA 252-265), (C-Term), (Intracellular) antibodyCALHM1 Reactivity: Human, Rat, Mouse WB, IHC, IF Host: Rabbit Polyclonal unconjugated
anti-Calcium Homeostasis Modulator 1 (CALHM1) (AA 252-265), (C-Term), (Intracellular) antibody (Atto 594)CALHM1 Reactivity: Human, Rat, Mouse IHC, IF, ICC Host: Rabbit Polyclonal Atto 594
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- Application Notes
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ELISA. Western Blot: CALHM1 antibody can be used for detection of CALHM1 at 1 - 2 μg/mL. Immunohistochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Restrictions
- For Research Use only
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- Concentration
- 1.0 mg/mL
- Buffer
- PBS containing 0.02 % Sodium Azide as preservative
- Preservative
- Sodium azide
- Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freezing and thawing.
- Storage
- 4 °C/-20 °C
- Storage Comment
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Target
- CALHM1 (Calcium Homeostasis Modulator 1 (CALHM1))
- Alternative Name
- CALHM1 / FAM26C (CALHM1 Products)
- Synonyms
- FAM26C antibody, Fam26c antibody, RGD1564891 antibody, EG546729 antibody, calcium homeostasis modulator 1 antibody, novel protein similar to vertebrate calcium homeostasis modulator protein family antibody, CALHM1 antibody, LOC557535 antibody, Calhm1 antibody
- Background
- Alzheimer's disease (AD) is a progressive neurodegenerative disorder characterized by a massive loss of neurons in several brain regions and by the presence of senile plaques comprised of aggregated amyloid-b (Ab) peptides produced by the endoproteolysis of the amyloid precursor protein (APP). The calcium homeostasis modulator 1 (CALHM1) is a recently identified multipass transmembrane glycoprotein that controls cytosolic Ca2+ concentration and Ab levels. While some studies suggest CALHM1 is significantly associated with risk of AD, other reports suggest there is no link. CALHM1 has been suggested to modulate the Ca2+-dependent proteolytic process of APP through controlling the level of cytosolic Ca2+.Synonyms: Calcium homeostasis modulator protein 1
- Gene ID
- 255022
- NCBI Accession
- NP_001001412
- UniProt
- Q8IU99
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