HIST1H2BA antibody
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- Target See all HIST1H2BA products
- HIST1H2BA (Histone Cluster 1, H2ba (HIST1H2BA))
- Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This HIST1H2BA antibody is un-conjugated
- Application
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- Characteristics
- Polyclonal Antibody
- Purification
- Antigen affinity purification
- Immunogen
- Synthetic peptide of human HIST1H2BA
- Isotype
- IgG
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anti-Histone Cluster 1, H2ba (HIST1H2BA) (acLys126) antibody
HIST1H2BA Reactivity: Human WB, ELISA Host: Rabbit Polyclonal unconjugated
anti-Histone Cluster 1, H2ba (HIST1H2BA) (AA 1-30), (N-Term) antibodyHIST1H2BA Reactivity: Human WB Host: Rabbit Polyclonal RB38815 unconjugated
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- Application Notes
- WB 1:500-1:2000, IHC 1:50-1:300, ELISA 1:5000-1:10000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1.98 mg/mL
- Buffer
- PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- HIST1H2BA (Histone Cluster 1, H2ba (HIST1H2BA))
- Alternative Name
- HIST1H2BA (HIST1H2BA Products)
- Synonyms
- H2BFU antibody, STBP antibody, TSH2B antibody, bA317E16.3 antibody, Th2b antibody, histone cluster 1 H2B family member a antibody, histone cluster 1, H2ba antibody, HIST1H2BA antibody, Hist1h2ba antibody
- Background
- The nucleosome, made up of four core histone proteins (H2A, H2B, H3, and H4), is the primary building block of chromatin. Originally thought to function as a static scaffold for DNA packaging, histones have now been shown to be dynamic proteins, undergoing multiple types of post-translational modifications, including acetylation, phosphorylation, methylation, and ubiquitination , acetylation of specific lysine residues creates docking sites that facilitate recruitment of many transcription and chromatin regulatory proteins that contain a bromodomain, which binds to acetylated lysine residues . Histone H2B is rapidly phosphorylated at irradiation-induced DNA damage foci in mouse embryonic fibroblasts .
- Molecular Weight
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Observed_MW: Refer to figures
Calculated_MW: 14 kDa
- UniProt
- Q96A08
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