MMACHC antibody (Center)
-
- Target See all MMACHC Antibodies
- MMACHC (Methylmalonic Aciduria (Cobalamin Deficiency) CblC Type, with Homocystinuria (MMACHC))
-
Binding Specificity
- Center
-
Reactivity
- Human, Mouse
-
Host
- Rabbit
-
Clonality
- Polyclonal
-
Conjugate
- This MMACHC antibody is un-conjugated
-
Application
- Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)
- Cross-Reactivity
- Cow (Bovine)
- Cross-Reactivity (Details)
- Bovine (90 %)
- Characteristics
-
Rabbit Polyclonal antibody to MMACHC (methylmalonic aciduria (cobalamin deficiency) cblC type, with homocystinuria)
MMACHC antibody [N1C2] - Purification
- Purified by antigen-affinity chromatography.
- Immunogen
- Recombinant protein encompassing a sequence within the center region of human MMACHC. The exact sequence is proprietary.
- Isotype
- IgG
-
anti-Methylmalonic Aciduria (Cobalamin Deficiency) CblC Type, with Homocystinuria (MMACHC) (AA 63-282) antibody
MMACHC Reactivity: Human WB, ELISA, IHC Host: Rabbit Polyclonal unconjugated
anti-Methylmalonic Aciduria (Cobalamin Deficiency) CblC Type, with Homocystinuria (MMACHC) (AA 63-282) antibodyMMACHC Reactivity: Human ELISA, IHC Host: Rabbit Polyclonal unconjugated
anti-Methylmalonic Aciduria (Cobalamin Deficiency) CblC Type, with Homocystinuria (MMACHC) (AA 239-267), (C-Term) antibodyMMACHC Reactivity: Human WB Host: Rabbit Polyclonal RB42667 unconjugated
anti-Methylmalonic Aciduria (Cobalamin Deficiency) CblC Type, with Homocystinuria (MMACHC) (AA 1-225) antibodyMMACHC Reactivity: Human WB Host: Rabbit Polyclonal unconjugated
anti-Methylmalonic Aciduria (Cobalamin Deficiency) CblC Type, with Homocystinuria (MMACHC) antibodyMMACHC Reactivity: Human WB, FACS Host: Mouse Monoclonal 6B5 unconjugated
anti-Methylmalonic Aciduria (Cobalamin Deficiency) CblC Type, with Homocystinuria (MMACHC) (AA 1-225) antibodyMMACHC Reactivity: Human WB Host: Mouse Polyclonal unconjugated
anti-Methylmalonic Aciduria (Cobalamin Deficiency) CblC Type, with Homocystinuria (MMACHC) (AA 190-239) antibodyMMACHC Reactivity: Human, Mouse, Rat, Rabbit, Cow, Dog, Guinea Pig, Horse, Bat, Monkey, Pig WB Host: Rabbit Polyclonal unconjugated
-
- Application Notes
- Suggested dilution Reference ICC/IF 1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections) 1:100-1:1000* Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceICC/IF1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections)1:100-1:1000* Western blot1:500-1:3000*
- Comment
-
Positive Control: 293T , A431 , H1299 , HeLaS3 , HepG2 , Raji , mouse brain
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- 0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.
- Preservative
- Thimerosal (Merthiolate)
- Precaution of Use
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
-
- Target
- MMACHC (Methylmalonic Aciduria (Cobalamin Deficiency) CblC Type, with Homocystinuria (MMACHC))
- Alternative Name
- MMACHC (MMACHC Products)
- Synonyms
- cblC antibody, RP11-291L19.3 antibody, RGD1310806 antibody, 1810037K07Rik antibody, methylmalonic aciduria (cobalamin deficiency) cblC type, with homocystinuria antibody, methylmalonic aciduria cblC type, with homocystinuria antibody, MMACHC antibody, Mmachc antibody
- Background
-
The exact function of the protein encoded by this gene is not known, however, its C-terminal region shows similarity to TonB, a bacterial protein involved in energy transduction for cobalamin (vitamin B12) uptake. Hence, it is postulated that this protein may have a role in the binding and intracellular trafficking of cobalamin. Mutations in this gene are associated with methylmalonic aciduria and homocystinuria type cblC.
- Molecular Weight
- 32 kDa
- Gene ID
- 25974
-
