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RENT2/UPF2 antibody (AA 1153-1272)

UPF2 Reactivity: Human WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6149941
  • Target See all RENT2/UPF2 (UPF2) Antibodies
    RENT2/UPF2 (UPF2) (UPF2 Regulator of Nonsense Transcripts 2 (UPF2))
    Binding Specificity
    • 7
    • 7
    • 6
    • 6
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1153-1272
    Reactivity
    • 24
    • 6
    • 6
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 23
    • 1
    Rabbit
    Clonality
    • 24
    Polyclonal
    Conjugate
    • 14
    • 2
    • 2
    • 2
    • 2
    • 2
    This RENT2/UPF2 antibody is un-conjugated
    Application
    • 21
    • 14
    • 13
    • 5
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Sequence
    GPPLGGGEGE AESADTMPFV MLTRKGNKQQ FKILNVPMSS QLAANHWNQQ QAEQEERMRM KKLTLDINER QEQEDYQEML QSLAQRPAPA NTNRERRPRY QHPKGAPNAD LIFKTGGRRR
    Cross-Reactivity
    Human, Mouse
    Characteristics
    Polyclonal Antibodies
    Immunogen
    Recombinant fusion protein containing a sequence corresponding to amino acids 1153-1272 of human UPF2 (NP_542166.1).
    Isotype
    IgG
  • Application Notes
    WB,1:500 - 1:2000
    Comment

    HIGH QUALITY

    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    RENT2/UPF2 (UPF2) (UPF2 Regulator of Nonsense Transcripts 2 (UPF2))
    Alternative Name
    UPF2 (UPF2 Products)
    Synonyms
    HUPF2 antibody, RENT2 antibody, smg-3 antibody, UPF2, regulator of nonsense mediated mRNA decay antibody, UPF2 regulator of nonsense transcripts homolog (yeast) antibody, UPF2 antibody, Upf2 antibody, upf2 antibody
    Background
    This gene encodes a protein that is part of a post-splicing multiprotein complex involved in both mRNA nuclear export and mRNA surveillance. mRNA surveillance detects exported mRNAs with truncated open reading frames and initiates nonsense-mediated mRNA decay (NMD). When translation ends upstream from the last exon-exon junction, this triggers NMD to degrade mRNAs containing premature stop codons. This protein is located in the perinuclear area. It interacts with translation release factors and the proteins that are functional homologs of yeast Upf1p and Upf3p. Two splice variants have been found for this gene, both variants encode the same protein.,UPF2,HUPF2,RENT2,smg-3,Epigenetics & Nuclear Signaling,UPF2
    Molecular Weight
    66 kDa/147 kDa
    Gene ID
    26019
    UniProt
    Q9HAU5
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