CHD5 antibody (AA 1600-1699)
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- Target See all CHD5 Antibodies
- CHD5 (Chromodomain Helicase DNA Binding Protein 5 (CHD5))
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Binding Specificity
- AA 1600-1699
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This CHD5 antibody is un-conjugated
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Application
- ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
- Cross-Reactivity
- Human
- Purification
- >95%, Protein G purified
- Immunogen
- Recombinant Human Chromodomain-helicase-DNA-binding protein 5 protein (1600-1699AA)
- Isotype
- IgG
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anti-Chromodomain Helicase DNA Binding Protein 5 (CHD5) (C-Term) antibody
CHD5 Reactivity: Human ELISA, IHC Host: Rabbit Polyclonal unconjugated
anti-Chromodomain Helicase DNA Binding Protein 5 (CHD5) (Internal Region) antibodyCHD5 Reactivity: Human ELISA, WB, IF, ICC Host: Rabbit Polyclonal unconjugated
anti-Chromodomain Helicase DNA Binding Protein 5 (CHD5) (Internal Region) antibodyVerified CHD5 Reactivity: Human ELISA, IF, FACS Host: Goat Polyclonal unconjugated
anti-Chromodomain Helicase DNA Binding Protein 5 (CHD5) (C-Term) antibodyCHD5 Reactivity: Human, Mouse WB, IF, ICC Host: Rat Monoclonal 5A10 unconjugated
anti-Chromodomain Helicase DNA Binding Protein 5 (CHD5) (AA 64-98) antibodyCHD5 Reactivity: Human WB Host: Rabbit Polyclonal RB54755 unconjugated
anti-Chromodomain Helicase DNA Binding Protein 5 (CHD5) (AA 712-896) antibodyCHD5 Reactivity: Human WB, IHC, ICC Host: Rabbit Polyclonal unconjugated
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- Application Notes
- Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200,
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 - Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Target
- CHD5 (Chromodomain Helicase DNA Binding Protein 5 (CHD5))
- Alternative Name
- CHD5 (CHD5 Products)
- Synonyms
- CHD-5 antibody, 4930532L22Rik antibody, AW060752 antibody, B230399N07Rik antibody, CHD5 antibody, chromodomain helicase DNA binding protein 5 antibody, potassium voltage-gated channel subfamily A regulatory beta subunit 2 antibody, CHD5 antibody, Chd5 antibody, chd5 antibody, KCNAB2 antibody
- Background
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Background: Chromatin-remodeling protein that binds DNA through histones and regulates gene transcription. May specifically recognize and bind trimethylated \'Lys-27\' (H3K27me3) and non-methylated \'Lys-4\' of histone H3. Plays a role in the development of the nervous system by activating the expression of genes promoting neuron terminal differentiation. In parallel, it may also positively regulate the trimethylation of histone H3 at \'Lys-27\' thereby specifically repressing genes that promote the differentiation into non-neuronal cell lineages. Tumor suppressor, it regulates the expression of genes involved in cell proliferation and differentiation. Downstream activated genes may include CDKN2A that positively regulates the p53/TP53 pathway, which in turn, prevents cell proliferation. In spermatogenesis, it probably regulates histone hyperacetylation and the replacement of histones by transition proteins in chromatin, a crucial step in the condensation of spermatid chromatin and the production of functional spermatozoa.
Aliases: ATP-dependent helicase CHD5 antibody, CHD 5 antibody, CHD-5 antibody, CHD5 antibody, CHD5_HUMAN antibody, Chromodomain-helicase-DNA-binding protein 5 antibody, DKFZp434N231 antibody, KIAA0444 antibody, RP1-233K16.2 antibody
- UniProt
- Q8TDI0
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