SS18L1 antibody (AA 47-396)
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- Target See all SS18L1 Antibodies
- SS18L1 (Synovial Sarcoma Translocation Gene On Chromosome 18-Like 1 (SS18L1))
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Binding Specificity
- AA 47-396
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This SS18L1 antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- Cross-Reactivity
- Human, Mouse
- Purification
- >95%, Protein G purified
- Immunogen
- Recombinant Human Calcium-responsive transactivator protein (47-396AA)
- Isotype
- IgG
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anti-Synovial Sarcoma Translocation Gene On Chromosome 18-Like 1 (SS18L1) antibody
SS18L1 Reactivity: Human, Mouse, Rat IHC, IF Host: Rabbit Polyclonal unconjugated
anti-Synovial Sarcoma Translocation Gene On Chromosome 18-Like 1 (SS18L1) (AA 272-300) antibodySS18L1 Reactivity: Human WB Host: Rabbit Polyclonal RB28071 unconjugated
anti-Synovial Sarcoma Translocation Gene On Chromosome 18-Like 1 (SS18L1) (AA 251-300) antibodySS18L1 Reactivity: Human, Mouse, Rat, Dog, Guinea Pig, Horse, Monkey, Chicken WB Host: Rabbit Polyclonal unconjugated
anti-Synovial Sarcoma Translocation Gene On Chromosome 18-Like 1 (SS18L1) (AA 200-396) antibodySS18L1 Reactivity: Human WB Host: Rabbit Polyclonal unconjugated
anti-Synovial Sarcoma Translocation Gene On Chromosome 18-Like 1 (SS18L1) (AA 90-270) antibodySS18L1 Reactivity: Human WB Host: Rabbit Polyclonal unconjugated
anti-Synovial Sarcoma Translocation Gene On Chromosome 18-Like 1 (SS18L1) (Middle Region) antibodySS18L1 Reactivity: Human, Mouse, Rat, Dog, Guinea Pig, Horse, Cow, Rabbit WB Host: Rabbit Polyclonal unconjugated
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- Application Notes
- Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200,
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 - Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Target
- SS18L1 (Synovial Sarcoma Translocation Gene On Chromosome 18-Like 1 (SS18L1))
- Alternative Name
- SS18L1 (SS18L1 Products)
- Synonyms
- crest antibody, CREST antibody, LP2261 antibody, A230053O16Rik antibody, SS18L1, nBAF chromatin remodeling complex subunit antibody, synovial sarcoma translocation gene on chromosome 18-like 1 antibody, synovial sarcoma translocation gene on chromosome 18-like 1 S homeolog antibody, SS18, nBAF chromatin remodeling complex subunit like 1 antibody, SS18L1 antibody, ss18l1 antibody, ss18l1.S antibody, Ss18l1 antibody
- Background
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Background: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity).
Aliases: Calcium-responsive transactivator antibody, CREST antibody, CREST_HUMAN antibody, KIAA0693 antibody, LP2261 antibody, MGC26711 antibody, MGC78386 antibody, sarcoma translocation gene on chromosome18like1 antibody, SS18 antibody, SS18-like protein 1 antibody, SS18L1 antibody, SS18L1 nBAF chromatin remodeling complex antibody, SSXT antibody, synovial sarcoma translocation antibody, synovial sarcoma translocation gene on chromosome 18-like 1 antibody, SYT homolog 1 antibody
- UniProt
- O75177
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