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FBXO2 antibody (AA 1-296)

FBXO2 Reactivity: Human ELISA, IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7152410
  • Target See all FBXO2 Antibodies
    FBXO2 (F-Box Protein 2 (FBXO2))
    Binding Specificity
    • 15
    • 11
    • 8
    • 7
    • 4
    • 2
    • 1
    • 1
    AA 1-296
    Reactivity
    • 29
    • 27
    • 5
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 38
    • 4
    Rabbit
    Clonality
    • 40
    • 2
    Polyclonal
    Conjugate
    • 18
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This FBXO2 antibody is un-conjugated
    Application
    • 42
    • 18
    • 14
    • 13
    • 13
    • 5
    • 3
    • 3
    • 1
    • 1
    ELISA, Immunohistochemistry (IHC)
    Cross-Reactivity
    Human
    Purification
    Antigen Affinity Purified
    Immunogen
    Recombinant Human F-box only protein 2 protein (1-296AA)
    Isotype
    IgG
  • Application Notes
    Recommended dilution: IHC:1:20-1:200,
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C,-80 °C
    Storage Comment
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target
    FBXO2 (F-Box Protein 2 (FBXO2))
    Alternative Name
    FBXO2 (FBXO2 Products)
    Synonyms
    FBG1 antibody, FBX2 antibody, Fbs1 antibody, NFB42 antibody, OCP1 antibody, Fbs2 antibody, Prpl4 antibody, F-box protein 2 antibody, FBXO2 antibody, Fbxo2 antibody
    Background

    Background: Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex that mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Involved in the endoplasmic reticulum-associated degradation pathway (ERAD) for misfolded lumenal proteins by recognizing and binding sugar chains on unfolded glycoproteins that are retrotranslocated into the cytosol and promoting their ubiquitination and subsequent degradation. Prevents formation of cytosolic aggregates of unfolded glycoproteins that have been retrotranslocated into the cytosol. Able to recognize and bind denatured glycoproteins, preferentially those of the high-mannose type (By similarity).

    Aliases: F box gene 1 antibody, F box only protein 2 antibody, F box protein 2 antibody, F box protein only 2 antibody, F-box only protein 2 antibody, FBG 1 antibody, FBG1 antibody, Fbs 1 antibody, Fbs1 antibody, Fbs2 antibody, FBX 2 antibody, FBX2 antibody, FBX2_HUMAN antibody, FBXO 2 antibody, FBXO2 antibody, Neural F box protein NFB42 antibody, Neural F-box protein, 42-KD, rat, homolog of antibody, NFB 42 antibody, NFB42 antibody, OCP1 antibody, organ of Corti protein 1 antibody, Prpl4 antibody

    UniProt
    Q9UK22
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