GATA4 antibody (pSer262)
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- Target See all GATA4 Antibodies
- GATA4 (GATA Binding Protein 4 (GATA4))
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Binding Specificity
- pSer262
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Reactivity
- Human, Rat, Mouse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This GATA4 antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
- Specificity
- Phospho-GATA4 (Ser262) Antibody detects endogenous levels of GATA4 only when phosphorylated at Serine 262.
- Predicted Reactivity
- Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus
- Purification
- The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.
- Immunogen
- A synthesized peptide derived from human GATA4 around the phosphorylation site of Ser262.
- Isotype
- IgG
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anti-GATA Binding Protein 4 (GATA4) (pSer105) antibody
GATA4 Reactivity: Human, Rat, Mouse WB, ELISA, IHC, IF, ICC Host: Rabbit Polyclonal unconjugated
anti-GATA Binding Protein 4 (GATA4) antibodyGATA4 Reactivity: Human WB, IHC Host: Rabbit Monoclonal unconjugated
anti-GATA Binding Protein 4 (GATA4) (AA 228-440) antibodyGATA4 Reactivity: Rat WB, IHC, ICC, IP Host: Rabbit Polyclonal unconjugated
anti-GATA Binding Protein 4 (GATA4) (AA 50-150) antibodyGATA4 Reactivity: Human WB, IHC, IF Host: Rabbit Polyclonal unconjugated
anti-GATA Binding Protein 4 (GATA4) (AA 201-442) antibodyGATA4 Reactivity: Human WB, IHC, ICC, IP Host: Rabbit Polyclonal unconjugated
anti-GATA Binding Protein 4 (GATA4) (AA 261-360) antibodyGATA4 Reactivity: Human, Rat, Mouse WB, ELISA, IHC (p), IF (cc), IF (p) Host: Rabbit Polyclonal unconjugated
anti-GATA Binding Protein 4 (GATA4) (AA 298-328), (C-Term) antibodyGATA4 Reactivity: Human WB, FACS Host: Rabbit Polyclonal RB13444 unconjugated
anti-GATA Binding Protein 4 (GATA4) (AA 330-380) antibodyGATA4 Reactivity: Human WB, IHC, IHC (p) Host: Rabbit Polyclonal unconjugated
anti-GATA Binding Protein 4 (GATA4) antibodyGATA4 Reactivity: Human, Rat WB, ELISA Host: Mouse Monoclonal 6H10 unconjugated
anti-GATA Binding Protein 4 (GATA4) (AA 343-442) antibodyGATA4 Reactivity: Human WB, ELISA Host: Mouse Monoclonal 6C6 unconjugated
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- Application Notes
- WB 1:500-1:2000, IF/ICC 1:100-1:500, IHC 1:50-1:500, ELISA(peptide) 1:20000-1:40000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20 °C. Stable for 12 months from date of receipt.
- Expiry Date
- 12 months
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- Target
- GATA4 (GATA Binding Protein 4 (GATA4))
- Alternative Name
- GATA4 (GATA4 Products)
- Background
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Description: Transcriptional activator that binds to the consensus sequence 5'-AGATAG-3' and plays a key role in cardiac development and function (PubMed:24000169, PubMed:27984724). In cooperation with TBX5, it binds to cardiac super-enhancers and promotes cardiomyocyte gene expression, while it downregulates endocardial and endothelial gene expression (PubMed:27984724). Involved in bone morphogenetic protein (BMP)-mediated induction of cardiac-specific gene expression. Binds to BMP response element (BMPRE) DNA sequences within cardiac activating regions (By similarity). Acts as a transcriptional activator of ANF in cooperation with NKX2-5 (By similarity). Promotes cardiac myocyte enlargement (PubMed:20081228). Required during testicular development (PubMed:21220346). May play a role in sphingolipid signaling by regulating the expression of sphingosine-1-phosphate degrading enzyme, spingosine-1-phosphate lyase (PubMed:15734735).
Gene: GATA4
- Molecular Weight
- 48kDa
- Gene ID
- 2626
- UniProt
- P43694
- Pathways
- Peptide Hormone Metabolism, Carbohydrate Homeostasis
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