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F-Box Protein 3 antibody (AA 276-376)

FBXO3 Reactivity: Human ELISA, WB, IHC, IF Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7152425
  • Target See all F-Box Protein 3 (FBXO3) Antibodies
    F-Box Protein 3 (FBXO3)
    Binding Specificity
    • 14
    • 8
    • 5
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 276-376
    Reactivity
    • 30
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human
    Host
    • 28
    • 2
    Rabbit
    Clonality
    • 30
    Polyclonal
    Conjugate
    • 13
    • 5
    • 4
    • 4
    • 2
    • 2
    This F-Box Protein 3 antibody is un-conjugated
    Application
    • 23
    • 20
    • 14
    • 3
    • 1
    • 1
    ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
    Cross-Reactivity
    Human, Mouse
    Purification
    >95%, Protein G purified
    Immunogen
    Recombinant Human F-box only protein 3 protein (276-376AA)
    Isotype
    IgG
    Top Product
    Discover our top product FBXO3 Primary Antibody
  • Application Notes
    Recommended dilution: WB:1:200-1:5000, IHC:1:20-1:200, IF:1:50-1:200,
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C,-80 °C
    Storage Comment
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target
    F-Box Protein 3 (FBXO3)
    Alternative Name
    FBXO3 (FBXO3 Products)
    Synonyms
    FBA antibody, FBX3 antibody, 1200002G09Rik antibody, 1700026K02Rik antibody, AI046358 antibody, Fba antibody, zgc:112485 antibody, DKFZp459H187 antibody, F-box protein 3 antibody, F-box protein 3 S homeolog antibody, FBXO3 antibody, Fbxo3 antibody, fbxo3.S antibody, fbxo3 antibody
    Background

    Background: Substrate recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex. Mediates the ubiquitination of HIPK2 and probably that of EP300, leading to rapid degradation by the proteasome. In the presence of PML, HIPK2 ubiquitination still occurs, but degradation is prevented. PML, HIPK2 and FBXO3 may act synergically to activate p53/TP53-dependent transactivation.

    Aliases: F Box G - Domain 3 antibody, F box only protein 3 antibody, F box protein 3 antibody, F box protein FBX3 antibody, F-box only protein 3 antibody, FBA antibody, FBX3 antibody, FBX3_HUMAN antibody, FBXO3 antibody

    UniProt
    Q9UK99
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