Phone:
+1 877 302 8632
Fax:
+1 888 205 9894 (Toll-free)
E-Mail:
orders@antibodies-online.com

TINF2 antibody (Internal Region)

TIN2 Reactivity: Human WB, ELISA, IF, ICC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6265586
  • Target See all TINF2 (TIN2) Antibodies
    TINF2 (TIN2) (TERF1 Interacting Nuclear Factor 2 (TIN2))
    Binding Specificity
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Internal Region
    Reactivity
    • 19
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human
    Host
    • 15
    • 5
    Rabbit
    Clonality
    • 17
    • 3
    Polyclonal
    Conjugate
    • 16
    • 2
    • 1
    • 1
    This TINF2 antibody is un-conjugated
    Application
    • 15
    • 12
    • 4
    • 2
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
    Specificity
    TINF2 Antibody detects endogenous levels of total TINF2.
    Predicted Reactivity
    Pig,Bovine,Horse,Sheep,Rabbit,Dog
    Purification
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogen
    A synthesized peptide derived from human TINF2, corresponding to a region within the internal amino acids.
    Isotype
    IgG
  • Application Notes
    WB 1:500-1:2000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20 °C. Stable for 12 months from date of receipt.
    Expiry Date
    12 months
  • Target
    TINF2 (TIN2) (TERF1 Interacting Nuclear Factor 2 (TIN2))
    Alternative Name
    TINF2 (TIN2 Products)
    Synonyms
    DKCA3 antibody, TIN2 antibody, AW552114 antibody, D14Wsu146e antibody, Tin2 antibody, TERF1 interacting nuclear factor 2 antibody, Terf1 (TRF1)-interacting nuclear factor 2 antibody, TINF2 antibody, Tinf2 antibody
    Background

    Description: Component of the shelterin complex (telosome) that is involved in the regulation of telomere length and protection. Shelterin associates with arrays of double-stranded TTAGGG repeats added by telomerase and protects chromosome ends, without its protective activity, telomeres are no longer hidden from the DNA damage surveillance and chromosome ends are inappropriately processed by DNA repair pathways. Plays a role in shelterin complex assembly. Isoform 1 may have additional role in tethering telomeres to the nuclear matrix.

    Gene: TINF2

    Molecular Weight
    53kDa
    Gene ID
    26277
    UniProt
    Q9BSI4
    Pathways
    Cell Division Cycle, Telomere Maintenance, Regulation of Carbohydrate Metabolic Process
You are here:
Support