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ALKBH5 antibody (Internal Region)

ALKBH5 Reactivity: Human, Mouse, Rat WB, ELISA, IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6259460
  • Target See all ALKBH5 Antibodies
    ALKBH5 (AlkB, Alkylation Repair Homolog 5 (ALKBH5))
    Binding Specificity
    • 15
    • 7
    • 6
    • 6
    • 6
    • 2
    • 1
    Internal Region
    Reactivity
    Human, Mouse, Rat
    Host
    • 38
    • 2
    Rabbit
    Clonality
    • 40
    Polyclonal
    Conjugate
    • 9
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This ALKBH5 antibody is un-conjugated
    Application
    • 18
    • 17
    • 13
    • 13
    • 4
    • 3
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    Specificity
    ALKBH5 Antibody detects endogenous levels of total ALKBH5.
    Predicted Reactivity
    Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken
    Purification
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogen
    A synthesized peptide derived from human ALKBH5, corresponding to a region within the internal amino acids.
    Isotype
    IgG
    Top Product
    Discover our top product ALKBH5 Primary Antibody
  • Application Notes
    WB 1:500-1:2000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Expiry Date
    12 months
  • Target
    ALKBH5 (AlkB, Alkylation Repair Homolog 5 (ALKBH5))
    Alternative Name
    ALKBH5 (ALKBH5 Products)
    Synonyms
    RGD1309496 antibody, ABH5 antibody, OFOXD antibody, OFOXD1 antibody, AW050020 antibody, AW215868 antibody, Abh5 antibody, E130207K11 antibody, Ofoxd antibody, alkB homolog 5, RNA demethylase antibody, alkB homolog 5, RNA demethylase L homeolog antibody, Alkbh5 antibody, alkbh5.L antibody, ALKBH5 antibody
    Background

    Description: Dioxygenase that demethylates RNA by oxidative demethylation: specifically demethylates N6-methyladenosine (m6A) RNA, the most prevalent internal modification of messenger RNA (mRNA) in higher eukaryotes (PubMed:23177736, PubMed:24778178, PubMed:24616105, PubMed:24489119). Can also demethylate N6-methyladenosine in single-stranded DNA (in vitro) (PubMed:24616105). Requires molecular oxygen, alpha-ketoglutarate and iron (PubMed:21264265, PubMed:23177736, PubMed:24778178, PubMed:24616105, PubMed:24489119). Demethylation of m6A mRNA affects mRNA processing and export (PubMed:23177736). Required for spermatogenesis (By similarity).

    Gene: ALKBH5

    Molecular Weight
    ?44 kDa
    Gene ID
    54890
    UniProt
    Q6P6C2
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