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RNF31 antibody (Middle Region)

RNF31 Reactivity: Human, Mouse, Rat, Rabbit, Dog, Cow, Guinea Pig, Horse WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2774753
  • Target See all RNF31 Antibodies
    RNF31 (Ring Finger Protein 31 (RNF31))
    Binding Specificity
    • 14
    • 9
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    Reactivity
    Human, Mouse, Rat, Rabbit, Dog, Cow, Guinea Pig, Horse
    Host
    • 45
    • 1
    Rabbit
    Clonality
    • 46
    Polyclonal
    Conjugate
    • 18
    • 5
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This RNF31 antibody is un-conjugated
    Application
    • 40
    • 20
    • 13
    • 4
    • 3
    • 3
    • 1
    • 1
    Western Blotting (WB)
    Sequence
    SLINAHSLDP ATLYEVEELE TATERYLHVR PQPLAGEDPP AYQARLLQKL
    Predicted Reactivity
    Cow: 93%, Dog: 93%, Guinea Pig: 100%, Horse: 86%, Human: 100%, Mouse: 92%, Rabbit: 100%, Rat: 100%
    Characteristics
    This is a rabbit polyclonal antibody against RNF31. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the middle region of human RNF31
    Top Product
    Discover our top product RNF31 Primary Antibody
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 1072 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Shibata, Tokunaga, Goto, Komatsu, Gohda, Saeki, Tanaka, Takahashi, Sawasaki, Inoue, Oshiumi, Seya, Nakano, Tanaka, Iwai, Inoue: "HTLV-1 Tax Induces Formation of the Active Macromolecular IKK Complex by Generating Lys63- and Met1-Linked Hybrid Polyubiquitin Chains." in: PLoS pathogens, Vol. 13, Issue 1, pp. e1006162, (2017) (PubMed).

    Lafont, Kantari-Mimoun, Draber, De Miguel, Hartwig, Reichert, Kupka, Shimizu, Taraborrelli, Spit, Sprick, Walczak: "The linear ubiquitin chain assembly complex regulates TRAIL-induced gene activation and cell death." in: The EMBO journal, Vol. 36, Issue 9, pp. 1147-1166, (2017) (PubMed).

    Kupka, De Miguel, Draber, Martino, Surinova, Rittinger, Walczak: "SPATA2-Mediated Binding of CYLD to HOIP Enables CYLD Recruitment to Signaling Complexes." in: Cell reports, Vol. 16, Issue 9, pp. 2271-80, (2016) (PubMed).

    Queisser, Dada, Deiss-Yehiely, Angulo, Zhou, Kouri, Knab, Liu, Stegh, DeCamp, Budinger, Chandel, Ciechanover, Iwai, Sznajder: "HOIL-1L functions as the PKCζ ubiquitin ligase to promote lung tumor growth." in: American journal of respiratory and critical care medicine, Vol. 190, Issue 6, pp. 688-98, (2014) (PubMed).

    Blackwell, Zhang, Workman, Ting, Iwai, Habelhah: "Two coordinated mechanisms underlie tumor necrosis factor alpha-induced immediate and delayed I?B kinase activation." in: Molecular and cellular biology, Vol. 33, Issue 10, pp. 1901-15, (2013) (PubMed).

    Liu, Chen, Cai, Wu, Chen, Wu, Sun, Chen: "MAVS recruits multiple ubiquitin E3 ligases to activate antiviral signaling cascades." in: eLife, Vol. 2, pp. e00785, (2013) (PubMed).

    Smit, Monteferrario, Noordermeer, van Dijk, van der Reijden, Sixma: "The E3 ligase HOIP specifies linear ubiquitin chain assembly through its RING-IBR-RING domain and the unique LDD extension." in: The EMBO journal, Vol. 31, Issue 19, pp. 3833-44, (2012) (PubMed).

    Sieber, Lange, Kollmorgen, Erhardt, Quaas, Gontarewicz, Sass, Tiegs, Kreienkamp: "Sharpin contributes to TNF? dependent NF?B activation and anti-apoptotic signalling in hepatocytes." in: PLoS ONE, Vol. 7, Issue 1, pp. e29993, (2012) (PubMed).

  • Target
    RNF31 (Ring Finger Protein 31 (RNF31))
    Alternative Name
    RNF31 (RNF31 Products)
    Synonyms
    RNF31 antibody, HOIP antibody, ZIBRA antibody, AL033293 antibody, BC031509 antibody, Flj10111 antibody, Paul antibody, mFLJ00217 antibody, ring finger protein 31 antibody, RNF31 antibody, rnf31 antibody, Rnf31 antibody
    Background
    PWP2 contains a RING finger, a motif present in a variety of functionally distinct proteins and known to be involved in protein-DNA and protein-protein interactions.The protein encoded by this gene contains a RING finger, a motif present in a variety of functionally distinct proteins and known to be involved in protein-DNA and protein-protein interactions.
    Alias Symbols: FLJ10111, FLJ23501, MGC19975, ZIBRA, HOIP
    Protein Interaction Partner: CCDC24, VASN, KRTAP9-2, TSSC4, UBC, SNRPC, PRKCA, AES, PITX1, KIF1A, SHARPIN, RBCK1, RNF31, MALT1, VCP, OTULIN, IRAK1, ESR1, Ikbkg, CCDC14, WRNIP1, AKAP8L, TRAF2, TNF, NDUFA8, BIRC2, NOD2, BIRC3, HCVgp1, SOCS3, SMAD3, NOS3, UBE2D3, UBE2D1, TNFAIP3, GFI1B,
    Protein Size: 1072
    Molecular Weight
    120 kDa
    Gene ID
    55072
    NCBI Accession
    NM_017999, NP_060469
    UniProt
    Q96EP0
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