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ADH4 antibody (C-Term)

ADH4 Reactivity: Human, Mouse WB, FACS, IHC (p) Host: Rabbit Polyclonal RB21606 unconjugated
Catalog No. ABIN654087
  • Target See all ADH4 Antibodies
    ADH4 (Alcohol Dehydrogenase 4 (Class II), pi Polypeptide (ADH4))
    Binding Specificity
    • 7
    • 7
    • 7
    • 5
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 319-348, C-Term
    Reactivity
    • 36
    • 11
    • 4
    • 2
    • 2
    • 1
    • 1
    Human, Mouse
    Host
    • 31
    • 5
    Rabbit
    Clonality
    • 34
    • 2
    Polyclonal
    Conjugate
    • 19
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ADH4 antibody is un-conjugated
    Application
    • 29
    • 19
    • 18
    • 12
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Purification
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogen
    This ADH4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 319-348 amino acids from the C-terminal region of human ADH4.
    Clone
    RB21606
    Isotype
    Ig Fraction
  • Application Notes
    WB: 1:1000. WB: 1:1000. IHC-P: 1:10~50. FC: 1:10~50
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Expiry Date
    6 months
  • Attignon, Leblanc, Le-Grand, Duval, Aggerbeck, Rouach, Blanc: "Novel roles for AhR and ARNT in the regulation of alcohol dehydrogenases in human hepatic cells." in: Archives of toxicology, Vol. 91, Issue 1, pp. 313-324, (2017) (PubMed).

    Renon, Legrand, Blanc, Daubigney, Bokobza, Mortreux, Paul, Delabar, Rouach, Andreau, Janel: "Impact of Dyrk1A level on alcohol metabolism." in: Biochimica et biophysica acta, Vol. 1862, Issue 9, pp. 1495-503, (2016) (PubMed).

  • Target
    ADH4 (Alcohol Dehydrogenase 4 (Class II), pi Polypeptide (ADH4))
    Alternative Name
    ADH4 (ADH4 Products)
    Synonyms
    ADH-2 antibody, Adh2 antibody, ADH-1 antibody, Ac1002 antibody, alcohol dehydrogenase 4 (class II), pi polypeptide antibody, alcohol dehydrogenase Adh4 antibody, ADH4 antibody, adh4 antibody, Adh4 antibody
    Background
    This gene encodes class II alcohol dehydrogenase 4 pi subunit, which is a member of the alcohol dehydrogenase family. Members of this enzyme family metabolize a wide variety of substrates, including ethanol, retinol, other aliphatic alcohols, hydroxysteroids, and lipid peroxidation products. Class II alcohol dehydrogenase is a homodimer composed of 2 pi subunits. It exhibits a high activity for oxidation of long-chain aliphatic alcohols and aromatic alcohols and is less sensitive to pyrazole. This gene is localized to chromosome 4 in the cluster of alcohol dehydrogenase genes.
    Molecular Weight
    40222
    Gene ID
    127
    NCBI Accession
    NP_000661
    UniProt
    P08319
    Pathways
    Transition Metal Ion Homeostasis
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