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PKMYT1 antibody (N-Term)

PKMYT1 Reactivity: Human, Mouse WB Host: Rabbit Polyclonal RB34667 unconjugated
Catalog No. ABIN657999
  • Target See all PKMYT1 Antibodies
    PKMYT1 (Protein Kinase, Membrane Associated tyrosine/threonine 1 (PKMYT1))
    Binding Specificity
    • 23
    • 15
    • 7
    • 7
    • 6
    • 6
    • 6
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 114-143, N-Term
    Reactivity
    • 87
    • 17
    • 1
    Human, Mouse
    Host
    • 85
    • 2
    Rabbit
    Clonality
    • 86
    • 1
    Polyclonal
    Conjugate
    • 24
    • 9
    • 8
    • 8
    • 5
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    This PKMYT1 antibody is un-conjugated
    Application
    • 75
    • 46
    • 13
    • 13
    • 11
    • 7
    • 7
    • 3
    • 3
    • 2
    • 1
    Western Blotting (WB)
    Purification
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogen
    This Mouse Pkmyt1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 114-143 amino acids from the N-terminal region of mouse Pkmyt1.
    Clone
    RB34667
    Isotype
    Ig Fraction
    Top Product
    Discover our top product PKMYT1 Primary Antibody
  • Application Notes
    WB: 1:1000. WB: 1:1000. WB: 1:1000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Mouse Pkmyt1 Antibody (N-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.
    Expiry Date
    6 months
  • Target
    PKMYT1 (Protein Kinase, Membrane Associated tyrosine/threonine 1 (PKMYT1))
    Alternative Name
    Pkmyt1 (PKMYT1 Products)
    Synonyms
    MYT1 antibody, 6230424P17 antibody, AW209059 antibody, Myt1 antibody, RGD1305434 antibody, myt1 antibody, protein kinase, membrane associated tyrosine/threonine 1 antibody, protein kinase, membrane associated tyrosine/threonine 1 S homeolog antibody, PKMYT1 antibody, pkmyt1 antibody, Pkmyt1 antibody, pkmyt1.S antibody
    Background
    Pkmyt1 acts as a negative regulator of entry into mitosis (G2 to M transition) by phosphorylation of the CDK1 kinase specifically when CDK1 is complexed to cyclins. Mediates phosphorylation of CDK1 predominantly on 'Thr-14'. Also involved in Golgi fragmentation. May be involved in phosphorylation of CDK1 on 'Tyr-15' to a lesser degree, however tyrosine kinase activity is unclear and may be indirect. May be a downstream target of Notch signaling pathway during eye development (By similarity).
    Molecular Weight
    54053
    Gene ID
    268930
    NCBI Accession
    NP_075545
    UniProt
    Q9ESG9
    Pathways
    Mitotic G1-G1/S Phases, M Phase
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