KLHL18 antibody (AA 451-550)
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- Target See all KLHL18 products
- KLHL18 (Kelch-Like 18 (KLHL18))
- Binding Specificity
- AA 451-550
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Reactivity
- Human, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This KLHL18 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunocytochemistry (ICC)
- Cross-Reactivity
- Human, Rat
- Predicted Reactivity
- Mouse,Horse
- Purification
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human KLHL18
- Isotype
- IgG
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- Application Notes
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WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Storage Comment
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- Expiry Date
- 12 months
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- Target
- KLHL18 (Kelch-Like 18 (KLHL18))
- Alternative Name
- KLHL18 (KLHL18 Products)
- Synonyms
- A930041K15 antibody, AW545966 antibody, kelch-like 18 antibody, kelch like family member 18 antibody, Klhl18 antibody, KLHL18 antibody
- Background
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Synonyms: Kelch-like protein 18, KLHL18, KIAA0795, OK/SW-cl.74
Background: KLHL18 is a 574 amino acid protein that is related to the Drosophila kelch protein, which is required to maintain actin organization in ovarian ring canals. Mutations affecting Kelch function result in failure of Kelch to associate with the ring canals and subsequent female sterility. Human KLHL18 protein contains six kelch repeats, one BACK (BTB/Kelch associated) domain and one BTB (POZ) domain. The BTB (Broad-Complex, Tramtrack and Bric a brac) domain, also known as the POZ (Poxvirus and Zinc finger) domain, is an N-terminal homodimerization domain that contains multiple copies of kelch repeats and/or C2H2-type zinc fingers. Proteins that contain BTB domains are thought to be involved in transcriptional regulation via control of chromatin structure and function. There are two isoforms of KLHL18 that are produced as a result of alternative splicing events.
- Gene ID
- 23276
- UniProt
- O94889
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