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DKK4 antibody (AA 19-224)

DKK4 Reactivity: Human WB, ELISA, IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7149891
  • Target See all DKK4 Antibodies
    DKK4 (Dickkopf Homolog 4 (Xenopus Laevis) (DKK4))
    Binding Specificity
    • 18
    • 8
    • 8
    • 7
    • 7
    • 6
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 19-224
    Reactivity
    • 61
    • 9
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 63
    • 3
    • 1
    Rabbit
    Clonality
    • 65
    • 2
    Polyclonal
    Conjugate
    • 25
    • 10
    • 8
    • 6
    • 6
    • 6
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This DKK4 antibody is un-conjugated
    Application
    • 59
    • 41
    • 32
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    Cross-Reactivity
    Human
    Purification
    Antigen Affinity Purified
    Immunogen
    Recombinant Human Dickkopf-related protein 4 protein (19-224AA)
    Isotype
    IgG
  • Application Notes
    Recommended dilution: WB:1:500-1:2000, IHC:1:20-1:200,
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C,-80 °C
    Storage Comment
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target
    DKK4 (Dickkopf Homolog 4 (Xenopus Laevis) (DKK4))
    Alternative Name
    DKK4 (DKK4 Products)
    Synonyms
    DKK-4 antibody, Dkk-4 antibody, RGD1563172 antibody, dickkopf WNT signaling pathway inhibitor 4 antibody, DKK4 antibody, Dkk4 antibody
    Background

    Background: Antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero-posterior axial patterning, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer disease (By similarity).

    Aliases: Dickkopf 4 antibody, Dickkopf gene 4 antibody, Dickkopf homolog 4 (Xenopus laevis) antibody, Dickkopf homolog 4 antibody, Dickkopf related protein 4 antibody, Dickkopf-4 antibody, Dickkopf-related protein 4 short form antibody, Dickkopf4 antibody, DKK 4 antibody, Dkk-4 antibody, DKK4 antibody, DKK4_HUMAN antibody, hDkk 4 antibody, hDkk-4 antibody, hDkk4 antibody, MGC129562 antibody, MGC129563 antibody

    UniProt
    Q9UBT3
    Pathways
    WNT Signaling
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